Symptom dimensions, clinical course and comorbidity in men and women with obsessive-compulsive disorder
MetadataShow full item record
The study aimed to compare male and female patients with obsessive-compulsive disorder (OCD) across symptom dimensions, clinical course and comorbidity. A cross-sectional study was undertaken with 858 adult OCD patients (DSM-IV) from the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders. Patients were evaluated using structured interviews, including the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) and the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I). The sample was composed of 504 women (58.7%) and 354 men (41.3%) with a mean age of 35.4 years-old (range: 18-77). Men were younger, more frequently single and presented more tics, social phobia and alcohol use disorders. Among men, symptom interference occurred earlier and symptoms of the sexual/religious dimension were more common and more severe. Conversely, women were more likely to present symptoms of the aggressive, contamination/cleaning and hoarding dimension and comorbidity with specific phobias, anorexia nervosa, bulimia, trichotillomania, skin picking and compulsive buying. In the logistic regression, female gender remained independently associated with the aggressive and contamination/cleaning dimensions. In both genders the aggressive dimension remained associated with comorbid post-traumatic stress disorder, the sexual/religious dimension with major depression and the hoarding dimension with tic disorders. Gender seems to be relevant in the determination of OCD clinical presentation and course and should be considered an important aspect when defining more homogeneous OCD subgroups. © 2012 Elsevier B.V.
How to cite this document
Showing items related by title, author, creator and subject.
de Mathis, Maria Alice; do Rosario, Maria Conceição; Diniz, Juliana Belo; Torres, Albina Rodrigues ; Shavitt, Roseli Gedanki; Ferrão, Ygor Arzeno; Fossaluza, Victor; de Bragança Pereira, Carlos Alberto; Miguel, Eurípedes Constantino (European Psychiatry, 2008) [Artigo]Purpose: This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset. Methods: Three hundred and thirty OCD patients were consecutively ...
Impulsive compulsivity in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome Kashyap, Himani; Fontenelle, Leonardo F.; Miguel, Euripedes C.; Ferrão, Ygor A.; Torres, Albina Rodrigues ; Shavitt, Roseli G.; Ferreira-Garcia, Rafael; Do Rosário, Maria C.; Yücel, Murat (Journal of Psychiatric Research, 2012) [Artigo]Although traditionally obsessive-compulsive disorder (OCD) and impulse control disorders (ICD) have represented opposing ends of a continuum, recent research has demonstrated a frequent co-occurrence of impulsive and ...
Eating disorders in patients with obsessive-compulsive disorder: Prevalence and clinical correlates Sallet, Paulo C.; Alvarenga, Pedro Gomes de; Ferrão, Ygor; Mathis, Maria Alice de; Torres, Albina Rodrigues ; Marques, Andrea; Hounie, Ana G.; Fossaluza, Victor; Rosario, Maria Conceição do; Fontenelle, Leonardo F. et al. (International Journal of Eating Disorders, 2010) [Artigo]Objective: The objective is to evaluate the prevalence and associated clinical characteristics of eating disorders (ED) in patients with obsessive-compulsive disorder (OCD). Method: This is a cross-sectional study comparing ...