Hemodynamic variables in piglets anesthetized with isoflurane or propofol, kept under spontaneous ventilation and FIO2 of 0.5

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dc.contributor.authorIdo, C. K. [UNESP]
dc.contributor.authorSilva, P. E.S.
dc.contributor.authorSilva, H. R.A. [UNESP]
dc.contributor.authorBiteli, E. G.F.
dc.contributor.authorCarneiro, R. L.
dc.contributor.authorLopes, P. C.F.
dc.contributor.authorGering, A. P.
dc.contributor.authorNunes, N. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFazenda da Aeronáutica de Pirassununga
dc.contributor.institutionUniversidade Paulista
dc.contributor.institutionUniversidade do Estado da Bahia
dc.contributor.institutionCentro Universitário de Jaguariúna
dc.contributor.institutionUniversidade Federal do Tocantins
dc.date.accessioned2020-12-12T01:13:46Z
dc.date.available2020-12-12T01:13:46Z
dc.date.issued2019-11-01
dc.description.abstractThis study aimed to evaluate comparatively the effects of propofol or isoflurane on hemodynamic variables in piglets that received inspired oxygen fraction (FIO2) of 0.5 under spontaneous ventilation. Therefore, sixteen piglets weighing 16±1.1kg, were randomly divided into two groups: GI (Isoflurane and FIO2 of 0.5) and GP (Propofol and FIO2 of 0.5). Heart rate (HR), systolic, diastolic and mean arterial pressure (SAP, DAP and MAP), central venous pressure (CVP), cardiac output (CO), mean pulmonary arterial pressure (mPAP) and mean capillary pulmonary pressure (mCPP) were assessed 40 minutes after anesthetic induction (T0), followed by 15 minutes intervals (from T15 to T60). The variables cardiac index (CI), stroke volume (SV), stroke index (SI), total peripheral resistance (TPR), total peripheral resistance index (TPRI), pulmonary vascular resistance (PVR), and pulmonary vascular resistance index (PVRI) were calculated. SAP and TPRI were significantly different between groups at T30 and T60 (P< 0.05) with higher GP values being recorded. There were no differences in the other variables, however, GP presented mean closer to normality on most of the analyzed variables. Therefore, we conclude that total intravenous anesthesia with propofol presented greater stability of the hemodynamic variables evaluated.en
dc.description.affiliationFaculdade de Ciências Agrárias e Veterinárias UNESP
dc.description.affiliationFazenda da Aeronáutica de Pirassununga
dc.description.affiliationUniversidade Paulista
dc.description.affiliationUniversidade do Estado da Bahia
dc.description.affiliationCentro Universitário de Jaguariúna
dc.description.affiliationUniversidade Federal do Tocantins
dc.description.affiliationUnespFaculdade de Ciências Agrárias e Veterinárias UNESP
dc.format.extent1846-1852
dc.identifierhttp://dx.doi.org/10.1590/1678-4162-10845
dc.identifier.citationArquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 71, n. 6, p. 1846-1852, 2019.
dc.identifier.doi10.1590/1678-4162-10845
dc.identifier.fileS0102-09352019000601846.pdf
dc.identifier.issn1678-4162
dc.identifier.issn0102-0935
dc.identifier.scieloS0102-09352019000601846
dc.identifier.scopus2-s2.0-85078759103
dc.identifier.urihttp://hdl.handle.net/11449/198469
dc.language.isoeng
dc.relation.ispartofArquivo Brasileiro de Medicina Veterinaria e Zootecnia
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCardiovascular
dc.subjectInhalation
dc.subjectIntravenous
dc.subjectOxygen
dc.subjectPigs
dc.titleHemodynamic variables in piglets anesthetized with isoflurane or propofol, kept under spontaneous ventilation and FIO2 of 0.5en
dc.typeArtigo
unesp.author.orcid0000-0003-2167-6010[1]
unesp.author.orcid0000-0002-2816-1944[2]
unesp.author.orcid0000-0003-4021-0996[3]
unesp.author.orcid0000-0002-3600-8587[4]
unesp.author.orcid0000-0001-5946-5169[5]
unesp.author.orcid0000-0002-0086-2896[6]
unesp.author.orcid0000-0001-7818-627X[7]
unesp.author.orcid0000-0002-1258-6972[8]

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