Relative antioxidant activity of Brazilian medicinal plants for gastrointestinal diseases

Página do item simplificado
dc.contributor.authorBonacorsi, Cibele [UNESP]
dc.contributor.authorda Fonseca, Luiz Marcos [UNESP]
dc.contributor.authorRaddi, Maria Stella G. [UNESP]
dc.contributor.authorKitagawa, Rodrigo R.
dc.contributor.authorSannomiya, Miriam
dc.contributor.authorVilegas, Wagner [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Espírito Santo (UFES)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T14:21:26Z
dc.date.available2014-05-20T14:21:26Z
dc.date.issued2011-09-16
dc.description.abstractThe free radical scavenging capacity of Brazilian medicinal plants and some of their constituents was examined in vitro using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) quantitative assay. Twelve medicinal plants, used to treat gastrointestinal disorders (Alchornea glandulosa, Alchornea triplinervia, Anacardium humile, Byrsonima crassa, Byrsonima cinera, Byrsonima intermedia, Davilla elliptica, Davilla nitida, Mouriri pusa, Qualea grandiflora, Qualea parviflora and Qualea multiflora), were selected because they showed antiulcerogenic activity in previous studies. The radical scavenging methanolic extracts activity demonstrated to be dose-dependent. The efficient concentration, which represents the amount of the antioxidant able of decrease the initial DPPH radical by 50%, vary from < 5 to 17.2 mu g/ml. The lowest efficient concentration values among the analyzed plant were shown by A. humile, B. crassa and Q. parviflora. Purified phenolic compounds (amentoflavone, (+)-catechin, methyl gallate, quercetin 3-O-alpha-L-arabinopyranoside, and quercetin 3-O-beta-D-galactopyranoside) were also tested and the greatest antioxidant activities were obtained with (+)-catechin and methyl gallate, similar to quercetin, a phenolic compound used as standard.en
dc.description.affiliationSão Paulo State Univ UNISEP, Dept Clin Anal, Sch Pharmaceut Sci, Araraquara, SP, Brazil
dc.description.affiliationUniversidade Federal do Espírito Santo (UFES), Dept Pharmaceut Sci, Vitoria, ES, Brazil
dc.description.affiliationUniv São Paulo, Sch Arts Sci & Humanities, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ UNESP, Dept Organ Chem, Inst Chem, Araraquara, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ UNISEP, Dept Clin Anal, Sch Pharmaceut Sci, Araraquara, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ UNESP, Dept Organ Chem, Inst Chem, Araraquara, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent4511-4518
dc.identifierhttp://www.academicjournals.org/jmpr/pdf/pdf2011/16Sept/Bonacorsi%20et%20al.pdf
dc.identifier.citationJournal of Medicinal Plants Research. Victoria Island: Academic Journals, v. 5, n. 18, p. 4511-4518, 2011.
dc.identifier.fileWOS000299778500019.pdf
dc.identifier.issn1996-0875
dc.identifier.orcid0000-0003-3032-2556
dc.identifier.urihttp://hdl.handle.net/11449/26400
dc.identifier.wosWOS:000299778500019
dc.language.isoeng
dc.publisherAcademic Journals
dc.relation.ispartofJournal of Medicinal Plants Research
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectBrazilian medicinal plantsen
dc.subjectantioxidant activityen
dc.subject2,2-diphenyl-1-picrylhydrazyl (DPPH)en
dc.subjectgastric ulcersen
dc.titleRelative antioxidant activity of Brazilian medicinal plants for gastrointestinal diseasesen
dc.typeArtigo
dcterms.licensehttp://www.academicjournals.org/Creative%20Common%20Attribution%20License.htm
dcterms.rightsHolderAcademic Journals
unesp.author.orcid0000-0003-3032-2556[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Química, Araraquarapt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentAnálises Clínicas - FCFpt

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
WOS000299778500019.pdf
Tamanho:
87.63 KB
Formato:
Adobe Portable Document Format
Baixar
Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Araraquara - FCF - Faculdade de Ciências Farmacêuticas
Artigos - Química Orgânica - IQ