EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA

Página do item simplificado
dc.contributor.authorGuimaraes, R. C.
dc.contributor.authorErdmann, V. A.
dc.contributor.institutionFREE UNIV BERLIN
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:21:00Z
dc.date.available2014-05-20T15:21:00Z
dc.date.issued1992-12-01
dc.description.abstractThe frequency of adenine mononucleotides (A), dinucleotides (AA) and clusters, and the positions of clusters, were studied in 502 molecules of the 5S rRNA.All frequencies were reduced in the evolutive lines of vertebrates, plants and fungi, in parallel with increasing organismic complexity. No change was observed in invertebrates. All frequencies were increased in mitochondria, plastids and mycoplasmas. The presumed relatives to the ancestors of the organelles, Rhodobacteria alfa and Cyanobacteria, showed intermediate values, relative to the eubacterial averages. Firmibacterid showed very high number of cluster sites.Clusters were more frequent in single-stranded regions in all organisms. The routes of organelles and mycoplasmas accummulated clusters at faster rates in double-stranded regions. Rates of change were higher for AA and clusters than for A in plants, vertebrates and organeltes, higher for cluster sites and A in mycoplasmas, and higher for AA and A in fungi. These data indicated that selection pressures acted more strongly on adenine clustering than on adenine frequency.It is proposed that AA and clusters, as sites of lower informational content. have the property of tolerating positional variation in the sites of other molecules (or other regions of the same molecule) that interact with the adenines. This reasoning was consistent with the degrees of genic polymorphism. low in plants and vertebrates and high in invertebrates. In the eubacteria endosymbiontic or parasitic to eukaryotes, the more tolerant RNA would be better adapted to interactions with the homologous nucleus-derived ribosomal proteins: the intermediate values observed in their precursors were interpreted as preadaptive.Among other groups, only the Deinococcus-Thermus eubacteria showed excessive AA and cluster contents, possibly related to their peculiar tolerance to mutagens, and the Ciliates showed excessive AA contents, indicative of retention of primitive characters.en
dc.description.affiliationFREE UNIV BERLIN,FACHBEREICH CHEM,INST BIOCHEM,W-1000 BERLIN 33,GERMANY
dc.format.extent13-45
dc.identifierhttp://ecb.thulb.uni-jena.de/receive/jportal_jparticle_00059861
dc.identifier.citationEndocytobiosis and Cell Research. Tubingen: Tubingen Univ Press Attempto Verlag, v. 9, n. 1, p. 13-45, 1992.
dc.identifier.issn0256-1514
dc.identifier.urihttp://hdl.handle.net/11449/32187
dc.identifier.wosWOS:A1992KN26200002
dc.language.isoeng
dc.publisherTubingen Univ Press Attempto Verlag
dc.relation.ispartofEndocytobiosis and Cell Research
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subject5S RIBOSOMAL-RNApt
dc.subjectEVOLUTIONpt
dc.subjectADENINE CLUSTERSpt
dc.subjectENDOSYMBIOSISpt
dc.subjectPARASITISMpt
dc.subjectPREADAPTATIONpt
dc.subjectCONVERGENCEpt
dc.subjectSIMPLIFICATIONpt
dc.subjectCOMPLEXITYpt
dc.titleEVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNAen
dc.typeArtigo
dcterms.rightsHolderTubingen Univ Press Attempto Verlag

Arquivos

Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos