Seqüência de moebius: Manifestações clínicas e avaliação auditiva

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dc.contributor.authorMartins, Regina Helena Garcia [UNESP]
dc.contributor.authorNakanishi, M. [UNESP]
dc.contributor.authorDias, N. H. [UNESP]
dc.contributor.authorSousa, J. C. [UNESP]
dc.contributor.authorTamashiro, I. A. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:20:18Z
dc.date.available2014-05-27T11:20:18Z
dc.date.issued2001-09-26
dc.description.abstractIntroduction: Children with Moebius syndrome may present paralysis of cranial nerves III, IV, V, VI, VII, VIII, IX, X and XII, compromising motor and sensorial functions. Hands and feet defects (syndactyly, equinovarus and arthrogryposis) are frequently associated. These manifestations can be attributed to the use of misoprostol during pregnancy to induce abortion. Study design: Clinical prospective. Aim: To evaluate the main clinical manifestations, hearing acuity and possible etiologic factors in children with Moebius syndrome. Material and method: The children were submitted to clinical, otolaryngological and hearing acuity assessment. Hearing acuity was evaluated through behavioral tests, pure tone audiometry, tympanometry and auditory brainstem response (ABR). We investigated possible etiologic factors. Results: Three boys and two girls were evaluated. The main manifestations were: facial paralysis, paralysis of masseter muscle, defects in dental occlusion, retraction of tympanic membrane, equinovarus, oblique palpebral fissure and tongue atrophy. Conductive hearing loss was detected in three children and sensorineural hearing loss in one child. The use of misoprostol during pregnancy was reported by four mothers. Conclusions: The children with Moebius syndrome evaluated in the present study manifested palsies of various cranial nerves, especially V, VII and XII nerves, responsible for motor and sensorial alterations. Inadequate eustachian tube function associated to conductive hearing loss was frequent. The use of misoprostol during pregnancy was reported by the mothers and it was considered a possible etiologic factor.en
dc.description.affiliationDepartamento de Oftalmologia Faculdade de Medicina de Botucatu UNESP, 18618-000 Botucatu/SP
dc.description.affiliationUnespDepartamento de Oftalmologia Faculdade de Medicina de Botucatu UNESP, 18618-000 Botucatu/SP
dc.format.extent440-446
dc.identifierhttp://www.bjorl.org/conteudo/acervo/acervo.asp?id=2784
dc.identifier.citationRevista Brasileira de Otorrinolaringologia, v. 67, n. 4, p. 440-446, 2001.
dc.identifier.issn0034-7299
dc.identifier.lattes8683290712226765
dc.identifier.scopus2-s2.0-17744401475
dc.identifier.urihttp://hdl.handle.net/11449/66585
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Otorrinolaringologia
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectABR
dc.subjectFacial palsy
dc.subjectHearing loss
dc.subjectMoebius syndrome
dc.subjectOtorhinolaryngology
dc.subjectmisoprostol
dc.subjectarthrogryposis
dc.subjectchild
dc.subjectconduction deafness
dc.subjectcranial nerve paralysis
dc.subjecteardrum
dc.subjectevoked brain stem auditory response
dc.subjectfacial nerve
dc.subjectfacial nerve paralysis
dc.subjectfoot malformation
dc.subjecthand malformation
dc.subjecthearing acuity
dc.subjecthearing impairment
dc.subjecthuman
dc.subjectmasseter muscle
dc.subjectpalpebral fissure anomaly
dc.subjectperception deafness
dc.subjectpes equinovarus
dc.subjectprenatal drug exposure
dc.subjectpure tone audiometry
dc.subjectsyndactyly
dc.subjecttongue disease
dc.subjecttooth occlusion
dc.subjecttrigeminal nerve
dc.subjecttympanometry
dc.subjectvestibulocochlear nerve
dc.titleSeqüência de moebius: Manifestações clínicas e avaliação auditivapt
dc.title.alternativeMoebius sequence: Clinical manifestations and hearing assessmenten
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rboto/paboutj.htm#copyright
unesp.author.lattes8683290712226765
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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