Publicação: Genomic characterization of canine circovirus detected in a dog with intermittent hemorrhagic gastroenteritis in Brazil
dc.contributor.author | Cruz, Taís Fukuta [UNESP] | |
dc.contributor.author | Batista, Thiago Neves | |
dc.contributor.author | Vieira, Ester Mariane | |
dc.contributor.author | Frediani Portela, Luiz Marcos [UNESP] | |
dc.contributor.author | Baccarin, Amanda Mahnke | |
dc.contributor.author | Gradiz, Jéssica Jehle | |
dc.contributor.author | Araújo Junior, João Pessoa [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | Universidade Regional de Blumenau (FURB) | |
dc.date.accessioned | 2020-12-12T02:06:36Z | |
dc.date.available | 2020-12-12T02:06:36Z | |
dc.date.issued | 2020-01-01 | |
dc.description.abstract | Because Canine circovirus (CanineCV) is a new species of the genus Circovirus, several issues related to its epidemiology, pathogenesis and clinical disease remain unknown. Thus, this study aimed to perform the characterization of the first complete genome sequence of CanineCV detected in a dog with diarrhea in Brazil. A stool sample was collected of a ten-month-old female German Shepherd dog which had signs of intermittent hemorrhagic gastroenteritis, vomiting, and a history of eating raw pork. The complete CanineCV genome was sequenced by Next-Generation Sequencing. The sequence had 2,063 nucleotides, showed a typical genomic organization for circovirus, and was grouped with strain 214 described in the United States by phylogenetic analysis. One amino acid change was found in the replicase protein, and because of that it was considered unique to CanineCV. Therefore, the characterization of the complete genome of Brazilian CanineCV can be used in future studies of molecular epidemiology, pathogenesis and development of diagnostic tools for the prevention and control of this disease. | en |
dc.description.affiliation | Departamento de Microbiologia e Imunologia Instituto de Biociências (IB) Universidade Estadual Paulista (Unesp) | |
dc.description.affiliation | Instituto de Biotecnologia (IBTEC) Universidade Estadual Paulista (Unesp) | |
dc.description.affiliation | Departamento de Medicina Veterinária Universidade Regional de Blumenau (FURB) | |
dc.description.affiliationUnesp | Departamento de Microbiologia e Imunologia Instituto de Biociências (IB) Universidade Estadual Paulista (Unesp) | |
dc.description.affiliationUnesp | Instituto de Biotecnologia (IBTEC) Universidade Estadual Paulista (Unesp) | |
dc.identifier | http://dx.doi.org/10.1590/0103-8478cr20190909 | |
dc.identifier.citation | Ciencia Rural, v. 50, n. 5, 2020. | |
dc.identifier.doi | 10.1590/0103-8478cr20190909 | |
dc.identifier.file | S0103-84782020000500451.pdf | |
dc.identifier.issn | 1678-4596 | |
dc.identifier.issn | 0103-8478 | |
dc.identifier.scielo | S0103-84782020000500451 | |
dc.identifier.scopus | 2-s2.0-85084978048 | |
dc.identifier.uri | http://hdl.handle.net/11449/200437 | |
dc.language.iso | eng | |
dc.relation.ispartof | Ciencia Rural | |
dc.rights.accessRights | Acesso aberto | |
dc.source | Scopus | |
dc.subject | Canine circovirus | |
dc.subject | Circovirus | |
dc.subject | Gastroenteritis | |
dc.subject | Genomic characterization | |
dc.title | Genomic characterization of canine circovirus detected in a dog with intermittent hemorrhagic gastroenteritis in Brazil | en |
dc.title | Caracterização genômica do Canine circovirus detectado em um cão com gastroenterite hemorrágica intermitente no Brasil | pt |
dc.type | Artigo | |
dspace.entity.type | Publication | |
unesp.campus | Universidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatu | pt |
unesp.department | Microbiologia e Imunologia - IBB | pt |
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