Genetic origin, admixture and population history of aurochs (Bos primigenius) and primitive European cattle

dc.contributor.authorUpadhyay, M. R.
dc.contributor.authorChen, W.
dc.contributor.authorLenstra, J. A.
dc.contributor.authorGoderie, C. R.J.
dc.contributor.authorMachugh, D. E.
dc.contributor.authorPark, S. D.E.
dc.contributor.authorMagee, D. A.
dc.contributor.authorMatassino, D.
dc.contributor.authorCiani, F.
dc.contributor.authorMegens, H. J.
dc.contributor.authorVan Arendonk, J. A.M.
dc.contributor.authorGroenen, M. A.M.
dc.contributor.authorMarsan, P. A.
dc.contributor.authorBalteanu, V.
dc.contributor.authorDunner, S.
dc.contributor.authorGarcia, J. F. [UNESP]
dc.contributor.authorGinja, C.
dc.contributor.authorKantanen, J.
dc.contributor.institutionWageningen University
dc.contributor.institutionSwedish Institute of Agricultural Sciences
dc.contributor.institutionUtrecht University
dc.contributor.institutionTaurus Foundation
dc.contributor.institutionUniversity College Dublin
dc.contributor.institutionTrinity Enterprise Centre
dc.contributor.institutionI FAO-GS AnGR
dc.contributor.institutionUniversitá Cattolica del Sacro Cuore
dc.contributor.institutionFaculty of Animal Science and Biotechnologies
dc.contributor.institutionUniversidade Complutense de Madrid
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade do Porto
dc.contributor.institutionUniversity of Eastern Finland
dc.description.abstractThe domestication of taurine cattle initiated ∼10 000 years ago in the Near East from a wild aurochs (Bos primigenius) population followed by their dispersal through migration of agriculturalists to Europe. Although gene flow from wild aurochs still present at the time of this early dispersion is still debated, some of the extant primitive cattle populations are believed to possess the aurochs-like primitive features. In this study, we use genome-wide single nucleotide polymorphisms to assess relationship, admixture patterns and demographic history of an ancient aurochs sample and European cattle populations, several of which have primitive features and are suitable for extensive management. The principal component analysis, the model-based clustering and a distance-based network analysis support previous works suggesting different histories for north-western and southern European cattle. Population admixture analysis indicates a zebu gene flow in the Balkan and Italian Podolic cattle populations. Our analysis supports the previous report of gene flow between British and Irish primitive cattle populations and local aurochs. In addition, we show evidence of aurochs gene flow in the Iberian cattle populations indicating wide geographical distribution of the aurochs. Runs of homozygosity (ROH) reveal that demographic processes like genetic isolation and breed formation have contributed to genomic variations of European cattle populations. The ROH also indicate recent inbreeding in southern European cattle populations. We conclude that in addition to factors such as ancient human migrations, isolation by distance and cross-breeding, gene flow between domestic and wild-cattle populations also has shaped genomic composition of European cattle populations.en
dc.description.affiliationAnimal Breeding and Genomics Centre Wageningen University, Droevendaalsesteeg 1
dc.description.affiliationDepartment of Animal Breeding and Genetics Swedish Institute of Agricultural Sciences
dc.description.affiliationFaculty of Veterinary Medicine Utrecht University
dc.description.affiliationTaurus Foundation
dc.description.affiliationAnimal Genomics Laboratory UCD School of Agriculture and Food Science University College Dublin
dc.description.affiliationUCD Conway Institute of Biomolecular and Biomedical Research University College Dublin
dc.description.affiliationIdentiGEN Ltd Unit 2 Trinity Enterprise Centre
dc.description.affiliationConsortium for Experimentation Dissemination and application of Innovative Biotechniques ConSDABI NFP I FAO-GS AnGR
dc.description.affiliationIstituto di Zootecnica Universitá Cattolica del Sacro Cuore
dc.description.affiliationUniversity of Agricultural Sciences and Veterinary Medicine Faculty of Animal Science and Biotechnologies
dc.description.affiliationFacultad de Veterinaria Universidade Complutense de Madrid
dc.description.affiliationDepartamento de Apoio Produção e Saúde Animal Faculdade de Medicina Veterinária de Araçatuba UNESP - Univ Estadual Paulista
dc.description.affiliationCIBIO-InBIO-Centro de Investigação em Biodiversidade e Recursos Genéticos Universidade do Porto Campus Agrário de Vairão
dc.description.affiliationUniversity of Eastern Finland
dc.description.affiliationUnespDepartamento de Apoio Produção e Saúde Animal Faculdade de Medicina Veterinária de Araçatuba UNESP - Univ Estadual Paulista
dc.identifier.citationHeredity, v. 118, n. 2, p. 169-176, 2017.
dc.rights.accessRightsAcesso restrito
dc.titleGenetic origin, admixture and population history of aurochs (Bos primigenius) and primitive European cattleen