Effects of Thermal Stress on Hepatic Melanomacrophages of Eupemphix nattereri (Anura)

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dc.contributor.authorDe Souza Santos, Lia Raquel
dc.contributor.authorFranco-Belussi, Lilian [UNESP]
dc.contributor.authorZieri, Rodrigo [UNESP]
dc.contributor.authorBorges, Rinneu Elias
dc.contributor.authorDe Oliveira, Classius [UNESP]
dc.contributor.institutionGoiano Fed Inst IFGoiano
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Rio Verde
dc.date.accessioned2014-12-03T13:08:54Z
dc.date.available2014-12-03T13:08:54Z
dc.date.issued2014-05-01
dc.description.abstractMelanomacrophages are the pigmented cells present in the hematopoietic organs. Besides melanin, hemosiderin and lipofuscin are also observed in the melanomacrophages. For the liver, however, numerous studies relate these cells to immunological and metabolic functions. Therefore, the aim of this study is to evaluate the hepatic metabolism by quantifying melanin, hemosiderin and lipofuscin in the anuran Eupemphix nattereri submitted to varying thermal conditions. E. nattereri adult males were separated into three groups, as follows: (i) five animals in the control group were kept at room temperature (27 degrees C); (ii) 30 animals were submitted to hyperthermic (35.1 degrees C); and (iii) 30 to hypothermic (18.9 degrees) conditions. In each experiment, the animals were analyzed and separated into two different treatments: (1) immediately after undergoing the stress; and, (2) after recovering from the stress caused by the stimulus, at three distinct times (12 hr, 24 hr, and 48 hr). Both hyperthermia and hypothermia decreased hepatic pigmentation after thermal stress. The recovered animals of both experimental treatments showed as much pigmentation as the control animals. Thermal stress alters hemosiderin and lipofuscin as well, which may be related to liver function catabolism. In conclusion, liver pigmentation decreased due to temperature variation and duration of thermal stimulation to which the animals were exposed. The increase in temperature rather than hypothermia led to more drastic physiological disorders. In this study, we observed that thermal stress for a short period compromises the morphology and liver function, as observed by the changing pigmentation of melanomacrophages. These analyses can be used as biomarkers of environmental effects. Anat Rec, 297:864-875, 2014. (c) 2014 Wiley Periodicals, Inc.en
dc.description.affiliationGoiano Fed Inst IFGoiano, Goiania, Go, Brazil
dc.description.affiliationSao Paulo State Univ UNESP, Grad Program Anim Biol, Dept Biol, Sao Paulo, Brazil
dc.description.affiliationSao Paulo State Univ UNESP, Dept Biol, Sao Paulo, Brazil
dc.description.affiliationUniv Rio Verde, Rio Verde, Go, Brazil
dc.description.affiliationUnespSao Paulo State Univ UNESP, Grad Program Anim Biol, Dept Biol, Sao Paulo, Brazil
dc.description.affiliationUnespSao Paulo State Univ UNESP, Dept Biol, Sao Paulo, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFUN-DUNESP
dc.description.sponsorshipIdFAPESP: 02/08016-9
dc.description.sponsorshipIdFAPESP: 05/02919-5
dc.description.sponsorshipIdFAPESP: 11/01840-7
dc.description.sponsorshipIdFAPESP: 13/02067-5
dc.description.sponsorshipIdCNPq: 475248/2007-4
dc.description.sponsorshipIdFUN-DUNESP01209/08-DFP
dc.format.extent864-875
dc.identifierhttp://dx.doi.org/10.1002/ar.22884
dc.identifier.citationAnatomical Record-advances In Integrative Anatomy And Evolutionary Biology. Hoboken: Wiley-blackwell, v. 297, n. 5, p. 864-875, 2014.
dc.identifier.doi10.1002/ar.22884
dc.identifier.issn1932-8486
dc.identifier.lattes5731856650217859
dc.identifier.orcid0000-0002-2029-7900
dc.identifier.urihttp://hdl.handle.net/11449/111706
dc.identifier.wosWOS:000334787000010
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofAnatomical Record-advances In Integrative Anatomy and Evolutionary Biology
dc.relation.ispartofjcr1.373
dc.relation.ispartofsjr0,766
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjecttemperatureen
dc.subjectliveren
dc.subjectpigmentationen
dc.subjectanuranen
dc.titleEffects of Thermal Stress on Hepatic Melanomacrophages of Eupemphix nattereri (Anura)en
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell
unesp.author.lattes5731856650217859[5]
unesp.author.orcid0000-0002-2029-7900[5]

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