Publicação:
INHIBITION OF BOVINE BRAIN ACETYLCHOLINESTERASE BY ALUMINUM

Página do item simplificado
dc.contributor.authorMoraes, M. S.
dc.contributor.authorLeite, SRA
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:29:21Z
dc.date.available2014-05-20T15:29:21Z
dc.date.issued1994-11-01
dc.description.abstractWe report the in vitro inhibitory effect of very low concentrations of aluminum salts (IC50 = 4.1 X 10(-12)M) on bovine brain acetylcholinesterase (AChE). The enzymatic assays were performed using acetylcholine bromide in a buffered pH 7.4 solution at 37 degrees C. The relevant enzyme interacting species is the Al3+ ion, whose concentrations were fixed at pM levels by a citrate metal ion buffer system. The IC50 demonstrates that Al3+ is a potent inhibitor of AChE.en
dc.description.affiliationUNESP,INST QUIM,BR-14800900 ARARAQUARA,BRAZIL
dc.description.affiliationUnespUNESP,INST QUIM,BR-14800900 ARARAQUARA,BRAZIL
dc.format.extent2635-2638
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_issues&pid=0100-879X&lng=en&nrm=iso
dc.identifier.citationBrazilian Journal of Medical and Biological Research. São Paulo: Associação Bras Divulg Cientifica, v. 27, n. 11, p. 2635-2638, 1994.
dc.identifier.issn0100-879X
dc.identifier.urihttp://hdl.handle.net/11449/38954
dc.identifier.wosWOS:A1994PQ37600017
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica (ABRADIC)
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.relation.ispartofjcr1.492
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectALUMINUMpt
dc.subjectACETYLCHOLINESTERASEpt
dc.subjectBRAINpt
dc.titleINHIBITION OF BOVINE BRAIN ACETYLCHOLINESTERASE BY ALUMINUMen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/bjmbr/iaboutj.htm
dcterms.rightsHolderAssociação Bras Divulg Cientifica
dspace.entity.typePublication

Arquivos

Licença do Pacote

Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos