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DNA viruses in human cancer: An integrated overview on fundamental mechanisms of viral carcinogenesis

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dc.contributor.authorOliveira, Deilson Elgui de [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:37:04Z
dc.date.available2014-05-20T13:37:04Z
dc.date.issued2007-03-18
dc.description.abstractThe first experimental data suggesting that neoplasm development in animals might be influenced by infectious agents were published in the early 1900s. However, conclusive evidence that DNA viruses play a role in the pathogenesis of some human cancers only emerged in the 1950s, when Epstein-Barr virus (EBV) was discovered within Burkitt lymphoma cells. Besides EBV, other DNA viruses consistently associated with human cancers are the hepatitis B virus (HBV), human papillomavirus (HPV), and Kaposi sarcoma herpesvirus (KSHV). Although each virus has unique features, it is becoming clearer that all these oncogenic agents target multiple cellular pathways to support malignant transformation and tumor development. (c) 2006 Elsevier B.V.. All rights reserved.en
dc.description.affiliationUniv Estadual Paulista, Dept Pathol, Botucatu Sch Med, São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Pathol, Botucatu Sch Med, São Paulo, Brazil
dc.format.extent182-196
dc.identifierhttp://dx.doi.org/10.1016/j.canlet.2006.05.010
dc.identifier.citationCancer Letters. Clare: Elsevier B.V., v. 247, n. 2, p. 182-196, 2007.
dc.identifier.doi10.1016/j.canlet.2006.05.010
dc.identifier.issn0304-3835
dc.identifier.lattes5240998569868081
dc.identifier.urihttp://hdl.handle.net/11449/12797
dc.identifier.wosWOS:000244995800002
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofCancer Letters
dc.relation.ispartofjcr6.491
dc.relation.ispartofsjr2,350
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectviral carcinogenesispt
dc.subjectDNA virusespt
dc.subjectcancerpt
dc.subjectEpstein-Barr viruspt
dc.subjectKaposi's sarcoma-associated viruspt
dc.subjecthuman papillomaviruspt
dc.subjectsimian virus 40 viruspt
dc.subjecthepatitis B viruspt
dc.titleDNA viruses in human cancer: An integrated overview on fundamental mechanisms of viral carcinogenesisen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.author.lattes5240998569868081
unesp.author.orcid0000-0001-5562-9648[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentPatologia - FMBpt

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Botucatu - FMB - Faculdade de Medicina