Mechanisms of action of fluoridated acidic liquid dentifrices against dental caries
Nenhuma Miniatura disponível
Data
2015-01-01
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Elsevier B.V.
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
Objective: This study attempted to clarify the mechanisms of action of fluoridated acidic liquid dentifrices against dental caries.Design: In the in vitro leg, enamel specimens were submitted to a pH-cycling model, treated with distinct dentifrices (0, 550 mu gF/g pH 4.5 and pH 7.0, 1100 or 5000 mu gF/g pH 7.0) and analyzed using hardness. Alkali-soluble fluoride (F) deposition was quantified on pre-demineralized specimens treated with the dentifrices. In the clinical leg, 2-to-4-year-old children who had been using liquid dentifrices for 6 months (550 mu gF/g pH 4.5 or pH 7.0 or 1100 mu gF/g pH 7.0) had their plaque samples collected 5 and 60 min after the last brushing. Fluoride uptake in whole plaque was evaluated.Results: The reduction of the pH had a partial preventive effect on subsurface hardness loss only. [F] had a significant influence on the deposition of fluoride, surface and subsurface hardness loss. In vivo, the reduction of the pH was able to significantly increase plaque F uptake, leading to similar levels as those found for the neutral dentifrice containing twice [F].Conclusion: The results obtained from in vitro studies whose design does not include the presence of dental plaque should be interpreted with caution. (C) 2014 Elsevier Ltd. All rights reserved.
Descrição
Palavras-chave
Idioma
Inglês
Como citar
Archives Of Oral Biology. Oxford: Pergamon-elsevier Science Ltd, v. 60, n. 1, p. 23-28, 2015.