Publicação:
Bronsted Acid Mediated Facile Greener Multicomponent Synthesis of 2,4-Diaryl-quinoline Derivatives in Water

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dc.contributor.authorMartins, Lucas Michelão [UNESP]
dc.contributor.authorMoreno, Vitor Fernandes [UNESP]
dc.contributor.authorRosário, Ilana Sganzerla [UNESP]
dc.contributor.authorGraeff, Carlos Frederico de Oliveira [UNESP]
dc.contributor.authorFilho, Luiz Carlos da Silva [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-03-01T23:39:59Z
dc.date.available2023-03-01T23:39:59Z
dc.date.issued2022-01-01
dc.description.abstractQuinolines are an important class of natural and synthetic products, with several biological activity and applications in medicine and electronics. In this work we present a greener method of synthesis of 2,4-diaryl-quinoline derivatives by an easy one-pot multicomponent reaction between aniline derivatives, aldehyde derivatives and phenylacetylene in water, with hydrochloric acid as promoter. With this method we could synthesize several compounds with good yield and reaction time, including new alkylamino-containing 2,4-diaryl-quinoline derivatives that could not be synthesized with niobium pentachloride catalyst in similar conditions.en
dc.description.affiliationDepartment of Physics São Paulo State University (UNESP) School of Sciences, Av. Eng. Luiz Edmundo Carrijo Coube, 14-01 São Paulo
dc.description.affiliationDepartment of Chemistry São Paulo State University (UNESP) School of Sciences, Av. Eng. Luiz Edmundo Carrijo Coube, 14-01 São Paulo
dc.description.affiliationUnespDepartment of Physics São Paulo State University (UNESP) School of Sciences, Av. Eng. Luiz Edmundo Carrijo Coube, 14-01 São Paulo
dc.description.affiliationUnespDepartment of Chemistry São Paulo State University (UNESP) School of Sciences, Av. Eng. Luiz Edmundo Carrijo Coube, 14-01 São Paulo
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 2013/07296-2
dc.description.sponsorshipIdFAPESP: 2016/01599-1
dc.description.sponsorshipIdFAPESP: 2018/09235-4
dc.description.sponsorshipIdFAPESP: 2018/14506-7
dc.description.sponsorshipIdCNPq: 302769/2018-8
dc.format.extent1-9
dc.identifierhttp://dx.doi.org/10.17807/orbital.v14i1.1689
dc.identifier.citationOrbital, v. 14, n. 1, p. 1-9, 2022.
dc.identifier.doi10.17807/orbital.v14i1.1689
dc.identifier.issn1984-6428
dc.identifier.scopus2-s2.0-85128398230
dc.identifier.urihttp://hdl.handle.net/11449/241744
dc.language.isoeng
dc.relation.ispartofOrbital
dc.sourceScopus
dc.subjectAcid catalyst
dc.subjectGreen synthesis
dc.subjectNitrogen heterocycles
dc.subjectQuinoline
dc.titleBronsted Acid Mediated Facile Greener Multicomponent Synthesis of 2,4-Diaryl-quinoline Derivatives in Wateren
dc.typeArtigo
dspace.entity.typePublication
unesp.departmentFísica - FCpt

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Bauru - FC - Faculdade de Ciências