Low back pain, obesity, and inflammatory markers: exercise as potential treatment

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dc.contributor.authorCruz Fernandes, Isabela Maia da [UNESP]
dc.contributor.authorPinto, Rafael Zambelli
dc.contributor.authorFerreira, Paulo
dc.contributor.authorLira, Fabio Santos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Minas Gerais (UFMG)
dc.contributor.institutionUniv Sydney
dc.date.accessioned2018-11-26T17:51:40Z
dc.date.available2018-11-26T17:51:40Z
dc.date.issued2018-04-01
dc.description.abstractLow back pain is a health issue with significant impact to patients and society. This narrative review aims to synthesize the relationship between obesity, low-grade inflammation and low back pain. It is known that a sedentary lifestyle is a risk factor for obesity and related disorders. The adipose tissue of obese people secretes a range of cytokines of character pro-and anti-inflammatory, with many molecular effects. In addition, pro-inflammatory cytokines are sensitizers of C-reactive protein (CRP), a marker of acute inflammation that can be linked to the musculoskeletal pain sensation individuals with back pain. Another inflammatory marker deserves mention, prostaglandin E-2. Prostaglandin E-2 is important in the process of triggering actions such as pyrexia, sen-sation of pain and inflammation, which are exhibited in low back pain condition. The potential for exercises and physical activity to control these mediators and act as a preventative measure for back pain are important because they work as a nonpharmacological strategy to this target audience. There are two types of exercise discussed in this review, the moderate-intensity continuous training and high-intensity interval training.en
dc.description.affiliationSao Paulo State Univ, Fac Sci & Technol, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente, SP, Brazil
dc.description.affiliationUniv Fed Minas Gerais, Dept Phys Therapy, Belo Horizonte, MG, Brazil
dc.description.affiliationUniv Sydney, Fac Hlth Sci, Discipline Physiotherapy, Sydney, NSW, Australia
dc.description.affiliationUnespSao Paulo State Univ, Fac Sci & Technol, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: SPRINT 2014/50672-8
dc.format.extent168-174
dc.identifierhttp://dx.doi.org/10.12965/jer.1836070.035
dc.identifier.citationJournal Of Exercise Rehabilitation. Seoul: Korean Soc Exercise Rehabilitation, v. 14, n. 2, p. 168-174, 2018.
dc.identifier.doi10.12965/jer.1836070.035
dc.identifier.issn2288-176X
dc.identifier.urihttp://hdl.handle.net/11449/164204
dc.identifier.wosWOS:000432448100004
dc.language.isoeng
dc.publisherKorean Soc Exercise Rehabilitation
dc.relation.ispartofJournal Of Exercise Rehabilitation
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectLow back pain
dc.subjectObesity
dc.subjectSedentary lifestyle
dc.subjectC-reactive protein
dc.subjectProstaglandins
dc.titleLow back pain, obesity, and inflammatory markers: exercise as potential treatmenten
dc.typeResenha
dcterms.rightsHolderKorean Soc Exercise Rehabilitation
unesp.departmentEstatística - FCTpt

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Presidente Prudente - FCT - Faculdade de Ciências e Tecnologia