Uveodermatologic syndrome in a Brazilian Fila dog

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dc.contributor.authorLaus, J. L.
dc.contributor.authorSousa, M. G.
dc.contributor.authorCabral, V. P.
dc.contributor.authorMamede, F. V.
dc.contributor.authorTinucci-Costa, M.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:25:47Z
dc.date.available2014-05-20T15:25:47Z
dc.date.issued2004-05-01
dc.description.abstractA 5-year-old Brazilian Fila dog was presented with a history of vision loss, alopecia, and generalized depigmentation of the skin and hair. Clinical examination confirmed generalized depigmentation and pyodermitis. on ophthalmic examination there was depigmentation at the eyelid mucocutaneous junction, associated with anterior uveitis, and bilateral posterior synechia at 360degrees. Both the complete blood count and skin scraping were normal. Skin biopsy showed histiocytary lichenoid interface dermatitis with an absence of pigment within the queratinocytes, and a moderate lymphomononuclear infiltrate and predominance of histiocytes in the papilar derma suggestive of uveodermatologic syndrome. Clinical management consisted of oral and topical administration of prednisone, associated with 1% indometacine eye drops. Methylprednisone was also used twice via the subconjunctival route, at an interval of 15 days. To prevent the development of secondary glaucoma due to posterior synechiae, dorzolamide and timolol eye drops were indicated. Both dermatologic and ophthalmic signs showed good improvement, vision was preserved, and some repigmentation of the skin and hair occurred.en
dc.description.affiliationSão Paulo State Univ, UNESP, Coll Agr & Vet Sci, Jaboticabal, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ, UNESP, Coll Agr & Vet Sci, Jaboticabal, SP, Brazil
dc.format.extent193-196
dc.identifierhttp://dx.doi.org/10.1111/j.1463-5224.2004.04023.x
dc.identifier.citationVeterinary Ophthalmology. Oxford: Blackwell Publishing Ltd, v. 7, n. 3, p. 193-196, 2004.
dc.identifier.doi10.1111/j.1463-5224.2004.04023.x
dc.identifier.issn1463-5216
dc.identifier.urihttp://hdl.handle.net/11449/36131
dc.identifier.wosWOS:000220888500010
dc.language.isoeng
dc.publisherBlackwell Publishing
dc.relation.ispartofVeterinary Ophthalmology
dc.relation.ispartofjcr1.083
dc.relation.ispartofsjr0,692
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectBrazilian Filapt
dc.subjectdepigmentationpt
dc.subjectdogpt
dc.subjectuveitispt
dc.subjectVogt-Koyanagi-Haradapt
dc.titleUveodermatologic syndrome in a Brazilian Fila dogen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderBlackwell Publishing Ltd
unesp.author.orcid0000-0003-1677-3641[5]
unesp.author.orcid0000-0003-1932-8818[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

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