Desnaturação de oxihemoglobinas humanas A, A2 e S pelo metodo de tampão isopropanol

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dc.contributor.authorNaoum, P. C.
dc.contributor.authorTeixeira, U. A.
dc.contributor.authorMachado, P. E. de Abreu
dc.contributor.authorMichelin, O. C.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-26T15:58:27Z
dc.date.available2014-05-26T15:58:27Z
dc.date.issued1978-12-01
dc.description.abstractHuman oxyhaemoglobin A and A2 from normal individuals and oxyhaemoglobin S from patients with sickle cell anaemia and sickle cell trait were studied using Isopropanol/buffer method at 37°C and 40°C. Hb S was less stable than Hb A, whereas Hb A2 was considerably more stable than either. Denaturation of Hb S was dependent on temperature and its concentration. Between the patients with sickle cell trait it was not possible to verify the influence of the concentration probably due to the small range used (from 38% to 44%).en
dc.format.extent241-244
dc.identifier.citationBrazilian Journal of Medical and Biological Research, v. 11, n. 4-5, p. 241-244, 1978.
dc.identifier.issn0100-879X
dc.identifier.scopus2-s2.0-0018141266
dc.identifier.urihttp://hdl.handle.net/11449/63442
dc.language.isoeng
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.relation.ispartofjcr1.492
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subject2 propanol
dc.subjecthemoglobin a
dc.subjecthemoglobin a2
dc.subjectblood and hemopoietic system
dc.subjecthuman cell
dc.subjectsickle cell anemia
dc.subjectsickle cell trait
dc.subject1-Propanol
dc.subjectBlood Protein Electrophoresis
dc.subjectBuffers
dc.subjectHeat
dc.subjectHemoglobin A
dc.subjectHemoglobin A2
dc.subjectHemoglobin, Sickle
dc.subjectHuman
dc.subjectOxyhemoglobins
dc.subjectProtein Denaturation
dc.titleDesnaturação de oxihemoglobinas humanas A, A2 e S pelo metodo de tampão isopropanolen
dc.title.alternativeThe denaturation of human oxyhaemoglobin A, A2 and S by isopropanol/buffer methoden
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/bjmbr/iaboutj.htm#Copyright

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