Novel Nanotechnology of TiO2 Improves Physical-Chemical and Biological Properties of Glass Ionomer Cement

dc.contributor.authorCibim, Daniela Dellosso
dc.contributor.authorSaito, Miki Taketomi
dc.contributor.authorGiovani, Priscila Alves
dc.contributor.authorSanches Borges, Ana Flavia
dc.contributor.authorArias Pecorari, Vanessa Gallego
dc.contributor.authorGomes, Orisson Ponce [UNESP]
dc.contributor.authorLisboa-Filho, Paulo Noronha [UNESP]
dc.contributor.authorNociti-Junior, Francisco Humberto
dc.contributor.authorPuppin-Rontani, Regina Maria
dc.contributor.authorKantovitz, Kamila Rosamilia
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionSao Leopoldo Mandic Inst
dc.description.abstractThe aim of this study was to assess the performance of glass ionomer cement (GIC) added with TiO2 nanotubes. TiO2 nanotubes [3%, 5%, and 7%(w/w)] were incorporated into GIC's (Ketac Molar EasyMix (TM)) powder component, whereas unblended powder was used as control. Physical-chemical-biological analysis included energy dispersive spectroscopy (EDS), surface roughness (SR), Knoop hardness (SH), fluoride-releasing analysis, cytotoxicity, cell morphology, and extracellular matrix (ECM) composition. Parametric or nonparametric ANOVA were used for statistical comparisons (alpha <= 0.05). Data analysis revealed that EDS only detected Ti at the 5% and 7% groups and that GIC's physical-chemical properties were significantly improved by the addition of 5% TiO2 as compared to 3% and GIC alone. Furthermore, regardless of TiO2 concentration, no significant effect was found on SR, whereas GIC-containing 7% TiO2 presented decreased SH values. Fluoride release lasted longer for the 5% and 7% TiO2 groups, and cell morphology/spreading and ECM composition were found to be positively affected by TiO2 at 5%. In conclusion, in the current study, nanotechnology incorporated in GIC affected ECM composition and was important for the superior microhardness and fluoride release, suggesting its potential for higher stress-bearing site restorations.en
dc.description.affiliationUniv Estadual Campinas, Piracicaba Dent Sch, Dept Pediat Dent, Piracicaba, SP, Brazil
dc.description.affiliationUniv Estadual Campinas, Piracicaba Dent Sch, Div Periodont, Dept Prosthodont & Periodont, Piracicaba, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Bauru Dent Sch, Dept Dent Endodont & Dent Mat, Bauru, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Sao Paulo, SP, Brazil
dc.description.affiliationState Univ Sao Paulo, Sch Sci, Dept Phys, Bauru, SP, Brazil
dc.description.affiliationSao Leopoldo Mandic Inst, Dent Res Ctr, Sao Paulo, SP, Brazil
dc.description.affiliationUnespState Univ Sao Paulo, Sch Sci, Dept Phys, Bauru, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 16/13786-0
dc.identifier.citationInternational Journal Of Biomaterials. London: Hindawi Ltd, 11 p., 2017.
dc.publisherHindawi Ltd
dc.relation.ispartofInternational Journal Of Biomaterials
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleNovel Nanotechnology of TiO2 Improves Physical-Chemical and Biological Properties of Glass Ionomer Cementen
dcterms.rightsHolderHindawi Ltd[7][7]


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