QTL affecting body weight in a candidate region of cattle chromosome 5

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Data

2003-01-01

Autores

Machado, Mariana B. B.
Alencar, Maurício M.
Pereira, Andréa P.
Oliveira, Henrique Nunes de [UNESP]
Casas, Eduardo
Coutinho, Luis L.
Regitano, Luciana C. A.

Título da Revista

ISSN da Revista

Título de Volume

Editor

Sociedade Brasileira de Genética

Resumo

The objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.

Descrição

Palavras-chave

QTL, growth traits, Microsatellite, Bovine

Como citar

Genetics and Molecular Biology. Sociedade Brasileira de Genética, v. 26, n. 3, p. 259-265, 2003.