QTL affecting body weight in a candidate region of cattle chromosome 5

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Machado, Mariana B. B.
Alencar, Maurício M.
Pereira, Andréa P.
Oliveira, Henrique Nunes de [UNESP]
Casas, Eduardo
Coutinho, Luis L.
Regitano, Luciana C. A.

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Sociedade Brasileira de Genética


The objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.



QTL, growth traits, Microsatellite, Bovine

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Genetics and Molecular Biology. Sociedade Brasileira de Genética, v. 26, n. 3, p. 259-265, 2003.