Calcifications in a clear cell mucoepidermoid carcinoma: a case report with histological and immunohistochemical findings

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dc.contributor.authordo Prado, Renata Falchete
dc.contributor.authorLima, Celina Faig
dc.contributor.authorRebelo Pontes, Helder Antonio
dc.contributor.authorAlmeida, Janete Dias
dc.contributor.authorGuimaraes Cabral, Luiz Antonio
dc.contributor.authorCarvalho, Yasmin Rodarte
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T15:28:49Z
dc.date.available2014-05-20T15:28:49Z
dc.date.issued2007-11-01
dc.description.abstractThe aim of this study was to report an unusual case of mucoepidermoid carcinoma (MEC) in a 39-year-old woman. The tumor showed a prominent population of clear and intermediate basal cells. Clear cells rarely predominate over other cell types. Such cases are called clear cell variant of MEC. The case also revealed a variable amount of calcified material in the tumor mass. Calcifications are rare in clear cell MEC. These structures were periodic acid- Schiff positive and diastase resistant, excluding glycogen origin. Immunohistochemistry was performed, and the epidermoid component was positive for cytokeratin (CK) 7, CK13, CK14, and CK19. The mucous and clear cells presented mild staining for CK7. Cytokeratins 7, 13, and 19 stained luminal cells, and intermediate cells exhibited positivity for CK7, CK14, and vimentin. The origin of the calcifications is speculated to be the result of dystrophic calcification of the amorphous eosinophilic material secreted by intermediate basal cells.en
dc.description.affiliationSão Paulo State Univ, Sch Dent, Dept Biosci & Oral Diag, BR-12245820 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Dent, Dept Stomatol, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Sch Dent, Dept Biosci & Oral Diag, BR-12245820 São Paulo, Brazil
dc.format.extentE40-E44
dc.identifierhttp://dx.doi.org/10.1016/j.tripleo.2007.06.001
dc.identifier.citationOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology. New York: Mosby-elsevier, v. 104, n. 5, p. E40-E44, 2007.
dc.identifier.doi10.1016/j.tripleo.2007.06.001
dc.identifier.issn1079-2104
dc.identifier.lattes9514297710569236
dc.identifier.lattes6967369119792151
dc.identifier.urihttp://hdl.handle.net/11449/38566
dc.identifier.wosWOS:000250921700028
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleCalcifications in a clear cell mucoepidermoid carcinoma: a case report with histological and immunohistochemical findingsen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.lattes9514297710569236
unesp.author.lattes6967369119792151
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, São José dos Campospt

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