Publicação: β-Ta2O5 thin film for implant surface modification triggers superior anti-corrosion performance and cytocompatibility of titanium
dc.contributor.author | Beline, Thamara | |
dc.contributor.author | de Almeida, Amanda B. | |
dc.contributor.author | Azevedo Neto, Nilton F. [UNESP] | |
dc.contributor.author | Matos, Adaias O. | |
dc.contributor.author | Ricomini-Filho, Antônio P. | |
dc.contributor.author | Sukotjo, Cortino | |
dc.contributor.author | Smeets, Paul J.M. | |
dc.contributor.author | da Silva, José H.D. [UNESP] | |
dc.contributor.author | Nociti, Francisco H. | |
dc.contributor.author | Barão, Valentim A.R. | |
dc.contributor.institution | Universidade Estadual de Campinas (UNICAMP) | |
dc.contributor.institution | Tribocorrosion and Nanomedicine (IBTN) | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | College of Dentistry | |
dc.contributor.institution | Northwestern University | |
dc.date.accessioned | 2020-12-12T01:20:36Z | |
dc.date.available | 2020-12-12T01:20:36Z | |
dc.date.issued | 2020-08-01 | |
dc.description.abstract | In this study, β-tantalum oxide (β-Ta2O5) thin film was synthesized via magnetron sputtering to improve the surface properties, cytocompatibility and electrochemical stability of titanium. X-ray diffraction analysis confirmed a crystalline orthorhombic phase of Ta2O5 film on the β-Ta2O5 experimental surface. A granular structure with a complex and hierarchical nature was demonstrated by atomic force microscopy. Ta2O5-treated surfaces exhibited greater roughness and hydrophilicity compared with untreated titanium discs (control). Enhanced electrochemical stability in simulated body fluid (pH 7.4) was noted for Ta2O5-treated surfaces wherein higher values of charge transfer resistance, nobler corrosion potential, and lower capacitance, corrosion current density, and corrosion rate values were observed vs untreated control. Real-time monitoring of albumin and fibrinogen proteins adsorption by an electrochemical quartz crystal microbalance disclosed similar protein interactions for control and Ta2O5-treated discs, with higher fibrinogen adsorption rates for Ta2O5-treated surfaces. Cell culture assays (MC3T3-E1 cells) demonstrated that Ta2O5-treated discs featured greater in vitro mineral nodule formation, normal cell morphology and spreading, and increased mRNA levels of runt-related transcription factor 2 (Runx-2), osteocalcin (Ocn), and collagen-1 (Col-1). Therefore, it can be concluded that β-Ta2O5 thin films may be considered a promising strategy to trigger superior long-term stability and biological properties of titanium implants. | en |
dc.description.affiliation | University of Campinas (UNICAMP) Piracicaba Dental School Department of Prosthodontics and Periodontics, Av. Limeira, 901 | |
dc.description.affiliation | Institute of Biomaterials Tribocorrosion and Nanomedicine (IBTN) | |
dc.description.affiliation | São Paulo State University (UNESP) School of Sciences Department of Physics, Av. Eng. Luís Edmundo C. Coube, 14-01 | |
dc.description.affiliation | University of Campinas (UNICAMP) Piracicaba Dental School Department of Physiological Science, Av. Limeira, 901 | |
dc.description.affiliation | University of Illinois at Chicago College of Dentistry Department of Restorative Dentistry, 801 S. Paulina | |
dc.description.affiliation | Department of Materials Science and Engineering Northwestern University | |
dc.description.affiliation | NUANCE Center Northwestern University | |
dc.description.affiliationUnesp | São Paulo State University (UNESP) School of Sciences Department of Physics, Av. Eng. Luís Edmundo C. Coube, 14-01 | |
dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | |
dc.description.sponsorship | W. M. Keck Foundation | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.description.sponsorship | Materials Research Science and Engineering Center, Harvard University | |
dc.description.sponsorshipId | FAPESP: 2016/07269-3 | |
dc.description.sponsorshipId | FAPESP: 2016/11470-6 | |
dc.description.sponsorshipId | FAPESP: 2017/18916-2 | |
dc.description.sponsorshipId | Materials Research Science and Engineering Center, Harvard University: NSF DMR-1720139 | |
dc.identifier | http://dx.doi.org/10.1016/j.apsusc.2020.146326 | |
dc.identifier.citation | Applied Surface Science, v. 520. | |
dc.identifier.doi | 10.1016/j.apsusc.2020.146326 | |
dc.identifier.issn | 0169-4332 | |
dc.identifier.scopus | 2-s2.0-85083268587 | |
dc.identifier.uri | http://hdl.handle.net/11449/198732 | |
dc.language.iso | eng | |
dc.relation.ispartof | Applied Surface Science | |
dc.source | Scopus | |
dc.subject | Biomaterials | |
dc.subject | Corrosion | |
dc.subject | Dental implants | |
dc.subject | Magnetron sputtering | |
dc.subject | Protein adsorption | |
dc.subject | Tantalum oxide | |
dc.title | β-Ta2O5 thin film for implant surface modification triggers superior anti-corrosion performance and cytocompatibility of titanium | en |
dc.type | Artigo | |
dspace.entity.type | Publication |