A novel biomagnetic approach to study caecocolonic motility in humans

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Data

2006-12-01

Autores

Romeiro, Fernando Gomes [UNESP]
Cora, L. A.
De Andreis, U.
Americo, M. F.
Oliveira, R. B.
Baffa, O.
Miranda, J. R. A.

Título da Revista

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Editor

Blackwell Publishing

Resumo

Motility patterns play a major role in human colonic functions; however, its physiological significance is poorly understood. Several studies have been introducing the Alternating Current Biosusceptometry (ACB) as a valuable tool in gastroenterology and pharmaceutical research. Using gold standard techniques, great effort has been made to validate ACB as a method for measuring gastrointestinal motility in humans and animals. The aim of this study was to evaluate caecocolonic motility and its response to a meal in healthy volunteers. The results showed a dominant frequency of 3.17 +/- 0.13 cycles per minute (mean +/- SD) that remained unchanged even after a standardized meal (P > 0.01). The colonic response to a meal was recorded as a considerable increase in amplitude, reflected by motility index (P < 0.01) and was observed for all the volunteers. The caecocolonic motility could be assessed by the ACB providing new insights into physiological patterns of motility. Moreover, the method is non-invasive, radiation-free, cost-effective and independent of bowel preparation.

Descrição

Palavras-chave

Alternating Current Biosusceptometry, biomagnetism, colonic motility, feeding response

Como citar

Neurogastroenterology and Motility. Oxford: Blackwell Publishing, v. 18, n. 12, p. 1078-1083, 2006.