A novel biomagnetic approach to study caecocolonic motility in humans
dc.contributor.author | Romeiro, Fernando Gomes [UNESP] | |
dc.contributor.author | Cora, L. A. | |
dc.contributor.author | De Andreis, U. | |
dc.contributor.author | Americo, M. F. | |
dc.contributor.author | Oliveira, R. B. | |
dc.contributor.author | Baffa, O. | |
dc.contributor.author | Miranda, J. R. A. | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | Universidade de São Paulo (USP) | |
dc.date.accessioned | 2014-05-20T13:32:53Z | |
dc.date.available | 2014-05-20T13:32:53Z | |
dc.date.issued | 2006-12-01 | |
dc.description.abstract | Motility patterns play a major role in human colonic functions; however, its physiological significance is poorly understood. Several studies have been introducing the Alternating Current Biosusceptometry (ACB) as a valuable tool in gastroenterology and pharmaceutical research. Using gold standard techniques, great effort has been made to validate ACB as a method for measuring gastrointestinal motility in humans and animals. The aim of this study was to evaluate caecocolonic motility and its response to a meal in healthy volunteers. The results showed a dominant frequency of 3.17 +/- 0.13 cycles per minute (mean +/- SD) that remained unchanged even after a standardized meal (P > 0.01). The colonic response to a meal was recorded as a considerable increase in amplitude, reflected by motility index (P < 0.01) and was observed for all the volunteers. The caecocolonic motility could be assessed by the ACB providing new insights into physiological patterns of motility. Moreover, the method is non-invasive, radiation-free, cost-effective and independent of bowel preparation. | en |
dc.description.affiliation | Univ Estadual Paulista, IBB, Lab Biomagnetismo, Dept Fis & Biofis, BR-18618000 São Paulo, Brazil | |
dc.description.affiliation | Univ Estadual Paulista, FMB, Dept Clin Med, BR-18618000 São Paulo, Brazil | |
dc.description.affiliation | Univ São Paulo, FMRP, Dept Clin Med, São Paulo, Brazil | |
dc.description.affiliation | Univ São Paulo, FFCLRP, Dept Fis & Matemat, São Paulo, Brazil | |
dc.description.affiliationUnesp | Univ Estadual Paulista, IBB, Lab Biomagnetismo, Dept Fis & Biofis, BR-18618000 São Paulo, Brazil | |
dc.description.affiliationUnesp | Univ Estadual Paulista, FMB, Dept Clin Med, BR-18618000 São Paulo, Brazil | |
dc.format.extent | 1078-1083 | |
dc.identifier | http://dx.doi.org/10.1111/j.1365-2982.2006.00838.x | |
dc.identifier.citation | Neurogastroenterology and Motility. Oxford: Blackwell Publishing, v. 18, n. 12, p. 1078-1083, 2006. | |
dc.identifier.doi | 10.1111/j.1365-2982.2006.00838.x | |
dc.identifier.file | WOS000242016400006.pdf | |
dc.identifier.issn | 1350-1925 | |
dc.identifier.uri | http://hdl.handle.net/11449/11239 | |
dc.identifier.wos | WOS:000242016400006 | |
dc.language.iso | eng | |
dc.publisher | Blackwell Publishing | |
dc.relation.ispartof | Neurogastroenterology and Motility | |
dc.relation.ispartofjcr | 3.842 | |
dc.relation.ispartofsjr | 2,095 | |
dc.rights.accessRights | Acesso aberto | |
dc.source | Web of Science | |
dc.subject | Alternating Current Biosusceptometry | pt |
dc.subject | biomagnetism | pt |
dc.subject | colonic motility | pt |
dc.subject | feeding response | pt |
dc.title | A novel biomagnetic approach to study caecocolonic motility in humans | en |
dc.type | Artigo | |
dcterms.license | http://olabout.wiley.com/WileyCDA/Section/id-406071.html | |
dcterms.rightsHolder | Blackwell Publishing | |
unesp.author.orcid | 0000-0001-8242-3653[2] | |
unesp.author.orcid | 0000-0002-0622-2814[6] | |
unesp.campus | Universidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatu | pt |
unesp.campus | Universidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatu | pt |
unesp.department | Clínica Médica - FMB | pt |
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