A novel biomagnetic approach to study caecocolonic motility in humans

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dc.contributor.authorRomeiro, Fernando Gomes [UNESP]
dc.contributor.authorCora, L. A.
dc.contributor.authorDe Andreis, U.
dc.contributor.authorAmerico, M. F.
dc.contributor.authorOliveira, R. B.
dc.contributor.authorBaffa, O.
dc.contributor.authorMiranda, J. R. A.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:32:53Z
dc.date.available2014-05-20T13:32:53Z
dc.date.issued2006-12-01
dc.description.abstractMotility patterns play a major role in human colonic functions; however, its physiological significance is poorly understood. Several studies have been introducing the Alternating Current Biosusceptometry (ACB) as a valuable tool in gastroenterology and pharmaceutical research. Using gold standard techniques, great effort has been made to validate ACB as a method for measuring gastrointestinal motility in humans and animals. The aim of this study was to evaluate caecocolonic motility and its response to a meal in healthy volunteers. The results showed a dominant frequency of 3.17 +/- 0.13 cycles per minute (mean +/- SD) that remained unchanged even after a standardized meal (P > 0.01). The colonic response to a meal was recorded as a considerable increase in amplitude, reflected by motility index (P < 0.01) and was observed for all the volunteers. The caecocolonic motility could be assessed by the ACB providing new insights into physiological patterns of motility. Moreover, the method is non-invasive, radiation-free, cost-effective and independent of bowel preparation.en
dc.description.affiliationUniv Estadual Paulista, IBB, Lab Biomagnetismo, Dept Fis & Biofis, BR-18618000 São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, FMB, Dept Clin Med, BR-18618000 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, FMRP, Dept Clin Med, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, FFCLRP, Dept Fis & Matemat, São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, IBB, Lab Biomagnetismo, Dept Fis & Biofis, BR-18618000 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, FMB, Dept Clin Med, BR-18618000 São Paulo, Brazil
dc.format.extent1078-1083
dc.identifierhttp://dx.doi.org/10.1111/j.1365-2982.2006.00838.x
dc.identifier.citationNeurogastroenterology and Motility. Oxford: Blackwell Publishing, v. 18, n. 12, p. 1078-1083, 2006.
dc.identifier.doi10.1111/j.1365-2982.2006.00838.x
dc.identifier.fileWOS000242016400006.pdf
dc.identifier.issn1350-1925
dc.identifier.urihttp://hdl.handle.net/11449/11239
dc.identifier.wosWOS:000242016400006
dc.language.isoeng
dc.publisherBlackwell Publishing
dc.relation.ispartofNeurogastroenterology and Motility
dc.relation.ispartofjcr3.842
dc.relation.ispartofsjr2,095
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectAlternating Current Biosusceptometrypt
dc.subjectbiomagnetismpt
dc.subjectcolonic motilitypt
dc.subjectfeeding responsept
dc.titleA novel biomagnetic approach to study caecocolonic motility in humansen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderBlackwell Publishing
unesp.author.orcid0000-0001-8242-3653[2]
unesp.author.orcid0000-0002-0622-2814[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentClínica Médica - FMBpt

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Artigos - Física e Biofísica - IBB
Botucatu - FMB - Faculdade de Medicina