Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus

dc.contributor.authorRossi, Bruna F. [UNESP]
dc.contributor.authorBonsaglia, Erika C. R. [UNESP]
dc.contributor.authorPantoja, Jose C. F. [UNESP]
dc.contributor.authorSantos, Marcos
dc.contributor.authorGoncalves, Juliano L.
dc.contributor.authorFernandes Junior, Ary [UNESP]
dc.contributor.authorRall, Vera L. M. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2021-06-25T12:40:48Z
dc.date.available2021-06-25T12:40:48Z
dc.date.issued2021-03-01
dc.description.abstractStaphylococcus aureus can elicit mild to more severe degrees of mastitis in cattle, depending on the response of the host's immune system and the virulence factors of the specific isolate. Several virulence factors are controlled by a global regulatory system, designated accessory gene regulator (agr). Thus, the objective was to examine associations between different capsular and agr types and the severity of bovine mastitis caused by S. aureus. All isolates were obtained from bovine subclinical (n = 50), mild clinical (n = 73), and moderate clinical mastitis cases (n = 28). Isolates containing the agrI gene and lacking the agr locus (agr(-)) were more prevalent among subclinical than clinical mastitis cases, whereas isolates containing the agrII and agrIII genes were more prevalent among clinical mastitis cases. The capsular types 5 (cap5) and 8 (cap8) were found in 42 and 44%, respectively, of the isolates obtained from subclinical cases and in 38.6 and 58.4%, respectively, of those isolated from clinical mastitis cases. Capsular type was not associated with type of mastitis (subclinical, mild clinical, or moderate clinical). We found a strong association between agr type and type of mastitis, suggesting that knowledge of S. aureus genetic profiles could be an additional tool to control this disease.en
dc.description.affiliationSao Paulo State Univ, Inst Biosci, Dept Chem & Biol Sci, Rua Dr Plinio Pinto e Silva, BR-18618691 Botucatu, SP, Brazil
dc.description.affiliationSao Paulo State Univ, Dept Anim Prod & Prevent Vet Med, Rua Prof Dr Walter Mauricio Correa, BR-18618681 Botucatu, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Sch Vet Med & Anim Sci, Dept Anim Nutr & Prod, Ave Duque Caxias Norte 225, BR-13635900 Pirassununga, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ, Inst Biosci, Dept Chem & Biol Sci, Rua Dr Plinio Pinto e Silva, BR-18618691 Botucatu, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ, Dept Anim Prod & Prevent Vet Med, Rua Prof Dr Walter Mauricio Correa, BR-18618681 Botucatu, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdCAPES: 001
dc.description.sponsorshipIdCNPq: 302383/2018-2
dc.format.extent3564-3568
dc.identifierhttp://dx.doi.org/10.3168/jds.2020-19275
dc.identifier.citationJournal Of Dairy Science. New York: Elsevier Science Inc, v. 104, n. 3, p. 3564-3568, 2021.
dc.identifier.doi10.3168/jds.2020-19275
dc.identifier.issn0022-0302
dc.identifier.urihttp://hdl.handle.net/11449/210138
dc.identifier.wosWOS:000630004500087
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofJournal Of Dairy Science
dc.sourceWeb of Science
dc.subjectcapsule
dc.subjectimmune system
dc.subjectStaphylococcus aureus
dc.subjectaccessory gene regulator (agr)
dc.titleShort communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureusen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.

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