Clinicopathological and prognostic profile of non-smoking and non-drinking head and neck cancer patients: a population-based comparative study

Página do item simplificado
dc.contributor.authorBonetti Valente, Vitor [UNESP]
dc.contributor.authorMantovan Mazzon, Bruna [UNESP]
dc.contributor.authorUrbano Collado, Francisco [UNESP]
dc.contributor.authorConrado Neto, Sebastião [UNESP]
dc.contributor.authorLúcia Marçal Mazza Sundefeld, Maria [UNESP]
dc.contributor.authorRicardo Biasoli, Éder [UNESP]
dc.contributor.authorIssamu Miyahara, Glauco [UNESP]
dc.contributor.authorGalera Bernabé, Daniel [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T08:40:32Z
dc.date.available2022-04-29T08:40:32Z
dc.date.issued2022-04-01
dc.description.abstractTobacco and alcohol consumption are the main risk factors for head and neck cancer (HNC). However, some individuals do not have a history of addiction and even so they develop the disease. This study evaluated clinicopathological and prognostic features of non-smoking and non-drinking (NSND) HNC patients. A sample of smoking and/or drinking (SD) HNC patients was used to explore the differences with NSND patients. Data were obtained from 667 patients with squamous cell carcinoma in oral cavity, oropharynx or larynx. The group of NSND individuals represented 12.6% of the HNC patients and had higher prevalence of women and elderly compared to SD group. Among NSND patients, most of them displayed tumors in oral cavity, advanced clinical staging and absence of second primary tumor. NSND HNC patients had higher tumor recurrence and increased overall and specific survival rates at 5-years follow-up. The NSND group showed higher prevalence of tumors in lips and alveolar ridge, lower rate of tumors in floor of mouth and no tumor in soft palate. NSND patients show a distinct profile from that found in SD patients. Clinicopathological features from NSND patients should be considered for HNC management.en
dc.description.affiliationOral Oncology Center São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo
dc.description.affiliationDepartment of Diagnosis and Surgery São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo
dc.description.affiliationUnespOral Oncology Center São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo
dc.description.affiliationUnespDepartment of Diagnosis and Surgery São Paulo State University (Unesp) School of Dentistry, 1193 José Bonifácio St, São Paulo
dc.identifierhttp://dx.doi.org/10.1016/j.oraloncology.2022.105799
dc.identifier.citationOral Oncology, v. 127.
dc.identifier.doi10.1016/j.oraloncology.2022.105799
dc.identifier.issn1879-0593
dc.identifier.issn1368-8375
dc.identifier.scopus2-s2.0-85125746941
dc.identifier.urihttp://hdl.handle.net/11449/230507
dc.language.isoeng
dc.relation.ispartofOral Oncology
dc.sourceScopus
dc.subjectAlcohol
dc.subjectClinicopathological features
dc.subjectHead and neck cancer
dc.subjectLarynx cancer
dc.subjectOral cancer
dc.subjectOropharynx cancer
dc.subjectPrognosis
dc.subjectRisk factors
dc.subjectSmoking
dc.subjectTobacco
dc.titleClinicopathological and prognostic profile of non-smoking and non-drinking head and neck cancer patients: a population-based comparative studyen
dc.typeCarta

Arquivos

Coleções

Araçatuba - COB - Centro de Oncologia Bucal