Avaliação histológica da biocompatibilidade do polímero da mamona no dorso nasal de macacos-pregos (Cebus apella)

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dc.contributor.authorDe Jesus Dias, Paulo Cesar
dc.contributor.authorGranato, Lidio
dc.contributor.authorDe Oliveira Ramalho, Lizeti De Toledo [UNESP]
dc.contributor.authorDe Oliveira, José Américo [UNESP]
dc.contributor.authorPretel, Hermes [UNESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionFaculdade de Ciências Médicas da Santa Casa de São Paulo
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T20:55:47Z
dc.date.available2022-04-28T20:55:47Z
dc.date.issued2009-01-01
dc.description.abstractBone tissue lesions can be caused by congenital and acquired factors, and result in nasal deformities with cosmetic and functional repercussion. Surgical treatment in these cases frequently requires complex reconstructions and the use of biomaterials. The polyurethane derived from castor beans (Ricinus communis) has a favorable formulation in terms of ease of processing, flexibility, no emission of toxic vapors and low cost. Nonetheless, despite favorable results, studies about the use of castor beam polymer (Ricinus communis) assessing tissue reaction on the nasal dorsum are still missing in the literature. Aim: the goal of the present investigation is to histologically assess the Ricinus communis polymer implant biocompatibility with the nasal dorsum. Study design: experimental. Materials and Methods: we used four Cebus appela monkeys, in which we created a nasal dorsal defect in all the animals and there we placed the aforementioned implant. The animals were sacrificed 270 days after surgery and the samples were submitted to histological study. Results: in the histology analysis we did not observe the presence of foreign body granulomas or phagocytic cells. We also observed a progressive bone formation and maturation. Conclusion: macroscopic and microscopic results showed that the castor oil polymer implant was biocompatible. © Revista Brasileira de Otorrinolaringologia.en
dc.description.affiliationUniversidade Federal de São Paulo
dc.description.affiliationDisciplina de Otorrinolaringologia Faculdade de Ciências Médicas da Santa Casa de São Paulo
dc.description.affiliationDepartamento de Morfologia Faculdade de Odontologia de Araraquara UNESP
dc.description.affiliationNúcleo de Procriação de Macacos -Prego Departamento de Ciências Básicas UNESP
dc.description.affiliationFaculdade de Odontologia de Araraquara UNESP Faculdade de Odontologia de Araraquara - UNESP
dc.description.affiliationUnespDepartamento de Morfologia Faculdade de Odontologia de Araraquara UNESP
dc.description.affiliationUnespNúcleo de Procriação de Macacos -Prego Departamento de Ciências Básicas UNESP
dc.description.affiliationUnespFaculdade de Odontologia de Araraquara UNESP Faculdade de Odontologia de Araraquara - UNESP
dc.format.extent350-355
dc.identifierhttp://dx.doi.org/10.1016/S1808-8694(15)30650-9
dc.identifier.citationBrazilian Journal of Otorhinolaryngology, v. 75, n. 3, p. 350-355, 2009.
dc.identifier.doi10.1016/S1808-8694(15)30650-9
dc.identifier.issn1808-8686
dc.identifier.issn1808-8694
dc.identifier.scopus2-s2.0-69349084288
dc.identifier.urihttp://hdl.handle.net/11449/225604
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofBrazilian Journal of Otorhinolaryngology
dc.sourceScopus
dc.subjectBiocompatible materials
dc.subjectCastor bean
dc.subjectNose
dc.subjectPolymers
dc.titleAvaliação histológica da biocompatibilidade do polímero da mamona no dorso nasal de macacos-pregos (Cebus apella)pt
dc.title.alternativeRicinus communis biocompatibility histological study in the nose of Cebus apella monkeysen
dc.typeArtigo

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