Application in hyperthermia treatment

Abstract

Plasmonic and magnetic silicon hybrids are suitable hyperthermia nanoagents owing to their ability to generate heat under an external stimulus in addition to their biocompatibility, limited aggregation, dielectric properties, and surface functionalization. In this chapter, a discussion will be provided the applications of plasmonic and magnetic silicon hybrid nanoparticles in hyperthermia treatments. We shall first introduce the fundamentals of nanoparticle heating with the mechanisms triggered by localized surface plasmon polaritons and alternating magnetic fields. The synthesis and characterization of plasmonic and magnetic silicon hybrid nanoparticles will then be described, including examples of promising hyperthermia nanoagents designed to possess a heating efficient conversion. The last topic deals with hyperthermia in vivo and in vitro applications for pathological diseases, especially those related to malignant tumor cells and bacterial infections.