Influence of rapid- and slow-rate resorption collagen membrane in maxillary sinus augmentation

dc.contributor.authorBresaola, Marco Dapievi
dc.contributor.authorMatsumoto, Mariza Akemi [UNESP]
dc.contributor.authorZahoui, Abbas
dc.contributor.authorBiguetti, Claudia Cristina
dc.contributor.authorNary-Filho, Hugo
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.abstractObjective: To evaluate the effects of low- and rapid-resorption-rate bioabsorbable collagen membranes in maxillary sinus augmentation procedure in rabbits considering Schneiderian membrane (SM) reaction and bone tissue formation. Materials and methods: Eighteen male adult rabbits underwent bilateral maxillary sinus augmentation with particulate bovine hydroxyapatite to be divided into three groups, as follows: Group C – control, no membrane; Group RR – rapid resorbable collagen membrane; and Group SR – slow-resorbable collagen membrane. The animals were euthanized after 30 and 120 days for specimen's removal to be prepared and analyzed under light microscopy, histomorphometry, and immunohistochemistry for Runx2 and VEGF labeling. Results: Histopathology evaluation presented similar healing pattern among the groups with a satisfactory response of SM, both at day 30 and day 120. Bone histomorphometry did not reveal significant differences among the groups, as well as immunohistochemistry analysis, which presented intense immunolabeling for both proteins in all groups. Conclusions: The presence of both membranes did not negatively interfere in bone formation and remodeling, and the focal mild inflammatory reaction caused by their degrading process did not impair the reconstructive procedure.en
dc.description.affiliationOral Biology Master's Program Sagrado Coração University USC
dc.description.affiliationDepartment of Basic Sciences State of São Paulo University – FOA/UNESP
dc.description.affiliationOral Biology Doctoral's Program Sagrado Coração University USC
dc.description.affiliationOral Biology Doctoral's Program Bauru School of Dentistry University of São Paulo – FOB/USP
dc.description.affiliationOral Biology Master's and Doctoral's Program Department of Oral Maxillofacial Surgery Sagrado Coração University USC
dc.description.affiliationUnespDepartment of Basic Sciences State of São Paulo University – FOA/UNESP
dc.identifier.citationClinical Oral Implants Research, v. 28, n. 3, p. 320-326, 2017.
dc.relation.ispartofClinical Oral Implants Research
dc.rights.accessRightsAcesso restrito
dc.subjectsinus floor elevation
dc.subjectwound healing
dc.titleInfluence of rapid- and slow-rate resorption collagen membrane in maxillary sinus augmentationen