A new tropane alkaloid and other constituents of Erythroxylum rimosum (Erythroxylaceae)

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dc.contributor.authorRibeiro, Erika M. de O.
dc.contributor.authorLima, Luciano S.
dc.contributor.authorDavid, Jorge M.
dc.contributor.authorVale, Ademir E. Do
dc.contributor.authorLopes, Lucia M.X. [UNESP]
dc.contributor.authorDavid, Juceni P.
dc.contributor.institutionUniversidade Federal da Bahia (UFBA)
dc.contributor.institutionInstituto Federal da Bahia
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:29:02Z
dc.date.available2014-05-27T11:29:02Z
dc.date.issued2013-05-01
dc.description.abstractA new tropane alkaloid, named the 7β-acetoxy-3β,6β- dibenzoyloxytropane (1), was isolated from a methanol extract of Erythroxylum rimosum O.E. Schulz leaves. Other known compounds were detected, including quercetin, kaempferol-3-O-α-l-arabinofuranoside, (+)-catechin, epicatechin, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-α- arabinopyranoside, quercetin-3-O-β-arabinopyranoside, quercetin-3-β- glucopyranoside, kaempferol, quercetin-3-O-β-galactopyranoside, β-sitosterol, α-amyrin, β-amyrin, and the ester derivatives of these two amyrins. Compound 1 exhibited weak inhibition of acetylcholinesterase. Structural identification was performed using IR, ESIHRMS and one- and two-dimensional NMR data analyses and confirmed by comparison with literature data. © 2013 Phytochemical Society of Europe.en
dc.description.affiliationInstituto de Química Universidade Federal da Bahia, 40170-290, Salvador, BA
dc.description.affiliationInstituto Federal da Bahia Campus Porto Seguro, 45810-000, Porto Seguro, BA
dc.description.affiliationFaculdade de Farmácia Universidade Federal da Bahia, 40170-290, Salvador, BA
dc.description.affiliationInstituto de Química de Araraquara Universidade Estadual Paulista, 14801-970, Araraquara, SP
dc.description.affiliationUnespInstituto de Química de Araraquara Universidade Estadual Paulista, 14801-970, Araraquara, SP
dc.format.extent232-235
dc.identifierhttp://dx.doi.org/10.1016/j.phytol.2013.02.008
dc.identifier.citationPhytochemistry Letters, v. 6, n. 2, p. 232-235, 2013.
dc.identifier.doi10.1016/j.phytol.2013.02.008
dc.identifier.issn1874-3900
dc.identifier.issn1876-7486
dc.identifier.scopus2-s2.0-84875024992
dc.identifier.urihttp://hdl.handle.net/11449/75231
dc.identifier.wosWOS:000318271400017
dc.language.isoeng
dc.relation.ispartofPhytochemistry Letters
dc.relation.ispartofjcr1.575
dc.relation.ispartofsjr0,634
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAcetylcholinesterase inhibition
dc.subjectErythroxylaceae
dc.subjectErythroxylum rimosum
dc.subjectFlavonoids
dc.subjectTriterpenes
dc.subjectTropane alkaloid
dc.subject7beta acetoxy 3beta,6beta dibenzoyloxytropane
dc.subjectacetylcholinesterase
dc.subjectalpha amyrin
dc.subjectbeta amyrin
dc.subjectcatechin
dc.subjectepicatechin
dc.subjectErythroxylum rimosum extract
dc.subjectester derivative
dc.subjectglucopyranoside
dc.subjectkaempferol
dc.subjectkaempferol 3 O alpha levo arabinofuranoside
dc.subjectkaempferol derivative
dc.subjectmethanol
dc.subjectplant extract
dc.subjectquercetin 3 beta glucopyranoside
dc.subjectquercetin 3 O alpha arabinofuranoside
dc.subjectquercetin 3 O alpha arabinopyranoside
dc.subjectquercetin 3 O beta galactopyranoside
dc.subjectquercetin derivative
dc.subjectsitosterol
dc.subjecttropane alkaloid
dc.subjectunclassified drug
dc.subjectcholinesterase inhibition
dc.subjectcontrolled study
dc.subjectdrug structure
dc.subjectelectrospray mass spectrometry
dc.subjectenzyme inhibition
dc.subjectheteronuclear multiple bond correlation
dc.subjectinfrared radiation
dc.subjectnuclear magnetic resonance
dc.subjectplant leaf
dc.subjectpriority journal
dc.subjectproton nuclear magnetic resonance
dc.subjectErythroxylum
dc.titleA new tropane alkaloid and other constituents of Erythroxylum rimosum (Erythroxylaceae)en
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
unesp.author.orcid0000-0002-3405-7609[5]

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