Miopatia do multicore: Análise histoquímica de uma família

Resumo

In this paper the authors describe three cases of multicore myopathy in the same family. Case J was a white 77-year-old patient with proximal muscular atrophy and weakness, global hypotonia and global hypoactive deep tendon reflexes. Motor and sensory conduction studies were normal in all limbs. EMG examination showed a myopathic pattern with frequent spontaneous activity consisting of fibrillations and positive sharp waves. Histochemical reactions showed typical oxidative alterations of multicore myopathy. Cases 2 and 3 were the son and the daughter of case 1 respectively. They were both non-symptomatic patients with minimal EMG and histochemical alterations. These three patients illustrated the great clinical variability of this condition.

Descrição

Palavras-chave

Minicore disease, Multicore disease, Myopathy

Como citar

Revista Brasileira de Neurologia, v. 34, n. 2, p. 55-58, 1998.