Morphological effects on the hard palatine mucosa of Calomys callosus submitted to experimental chronic alcoholism

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dc.contributor.authorMartinez, M.
dc.contributor.authorMartinez, F. E.
dc.contributor.authorDa Cunha, M. R.
dc.contributor.authorSegatelli, T. M.
dc.contributor.authorPinheiro, P. F.F.
dc.contributor.authorAlmeida, C. C.D.
dc.contributor.institutionFed. University of São Carlos
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.date.accessioned2022-04-29T08:42:45Z
dc.date.available2022-04-29T08:42:45Z
dc.date.issued2002-01-01
dc.description.abstractThe morphological effects of ethanol ingestion on the hard palatine mucosa of adult male Calomys callosus were observed. Twenty rodents were divided into two experimental groups: the control group received solid diet, Purina rat chow, and tap water ad libitum; the alcoholic group received the same solid diet and ethanol P.A. diluted 20% in water (v/v). After 270 days of treatment, all animals were sacrificed and the hard palatine mucosa were prepared for TEM and SEM methods. The epithelial cells of the alcoholic group showed some alterations like cytoplasmatic lipid droplets, pycnotic nucleus and increased mitochondrial size. The lamina propria also presented intense lipid droplets accumulation. The morphological changes suggested that chronic ethanol consumption was able to modify the integrity of the mucosa.en
dc.description.affiliationDept. of Morphology and Pathology Fed. University of São Carlos, SP
dc.description.affiliationDepartment of Anatomy State University of São Paulo, Botucatu, SP
dc.description.affiliationDepartment of Anatomy University of Campinas, SP
dc.description.affiliationDepto. de Morfologia e Patologia Univ. Federal de São Carlos, Rod. Washington Luis Km 235 s/no, CEP 13.565.905, São Carlos, SP
dc.format.extent77-83
dc.identifier.citationJournal of Submicroscopic Cytology and Pathology, v. 34, n. 1, p. 77-83, 2002.
dc.identifier.issn1122-9497
dc.identifier.scopus2-s2.0-0036359950
dc.identifier.urihttp://hdl.handle.net/11449/230920
dc.language.isoeng
dc.relation.ispartofJournal of Submicroscopic Cytology and Pathology
dc.sourceScopus
dc.subjectAlcoholism
dc.subjectEpithelium
dc.subjectLamina propria
dc.subjectPalatine mucosa
dc.titleMorphological effects on the hard palatine mucosa of Calomys callosus submitted to experimental chronic alcoholismen
dc.typeArtigo

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