Effects of resistance exercise training on bone physical and mineral properties in rats submitted to growth hormone intervention

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dc.contributor.authorCastoldi, Robson Chacon [UNESP]
dc.contributor.authorGiometti, Ines Cristina
dc.contributor.authorOzaki, Guilherme Akio Tamura [UNESP]
dc.contributor.authorGarcia, Thiago Alves [UNESP]
dc.contributor.authordos Santos Pereira, João Domingos Augusto [UNESP]
dc.contributor.authorRubira, Rafael Jesus Gonçalves [UNESP]
dc.contributor.authorConstantino, Carlos José Leopoldo [UNESP]
dc.contributor.authorde Oliveira Júnior, Silvio Assis
dc.contributor.authorLouzada, Mario Jefferson Quirino
dc.contributor.authorBelangero, William Dias
dc.contributor.authorSilva Camargo Filho, José Carlos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade do Oeste Paulista – UNOESTE
dc.contributor.institutionUniversidade Federal de Mato Grosso do Sul (UFMS)
dc.contributor.institutionCatholic Salesian Auxilium University Centre
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.date.accessioned2023-07-29T16:01:31Z
dc.date.available2023-07-29T16:01:31Z
dc.date.issued2023-01-01
dc.description.abstractPurpose: To investigate the effects of applying growth hormone (GH) and performing a strength training protocol on mineralization, rigidity, and crystallinity on the bone tissue of Wistar rats. Method: In total, 40 male animals, 60 days old, of the Wistar lineage were used, distributed into four groups: control (C) [n = 10], control and application of GH (GHC) [n = 10], resistance training (T) [n = 10], and resistance training and application of GH (GHT) [n = 10]. The training period lasted four weeks and consisted of four sets of 10 jumps in a liquid medium. The amount of 0.2 IU per kilogram of body mass (0.2 IU/Kg) of GH was administered in the GHC and GHT groups. After the experimental period, samples of the tibia were collected and analyzed using Raman Spectroscopy (633 nm), Bone Densitometry - dual-energy x-ray absorptiometry (DXA), and Mechanical Assay (F-max). Results: The GHT group presented an increase for the variable Amide II (1544 cm-1) and decrease for the variable Proline (727 cm-1) from the Raman Spectroscopy analysis (p < 0.05). In addition, an increase was observed for the variables bone mineral density (BMD) and bone mineral content (BMC) (p < 0.05). Finally, no statistically significant differences were observed for the variables mineralization, crystallinity, phosphate carbonate types A and B, and bone rigidity (p > 0.05). Conclusion: It is concluded that GH added to RT resulted in an increase in the mineral Amide II (1544 cm-1) and a decrease in Proline (727 cm-1). Furthermore, an increase in BMD and BMC was observed only in the GHT group. Finally, no alterations were observed in crystallinity and rigidity in the different groups of animals.en
dc.description.affiliationDepartment of Physical Therapy Universidade Estadual Paulista “Júlio de Mesquita Filho” – UNESP, State of São Paulo
dc.description.affiliationFaculty of Veterinary Medicine Universidade do Oeste Paulista – UNOESTE, State of São Paulo
dc.description.affiliationDepartment of Physics Chemistry and Biology Universidade Estadual Paulista “Júlio de Mesquita Filho” – UNESP, State of São Paulo
dc.description.affiliationPostgraduate Program in Movement Sciences Federal University of Mato Grosso do Sul – UFMS
dc.description.affiliationCatholic Salesian Auxilium University Centre, São Paulo
dc.description.affiliationFaculty of Medical Sciences State University of Campinas – UNICAMP, São Paulo State
dc.description.affiliationUnespDepartment of Physical Therapy Universidade Estadual Paulista “Júlio de Mesquita Filho” – UNESP, State of São Paulo
dc.description.affiliationUnespDepartment of Physics Chemistry and Biology Universidade Estadual Paulista “Júlio de Mesquita Filho” – UNESP, State of São Paulo
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 2018/22214-6
dc.description.sponsorshipIdCNPq: 2020/05423-0
dc.identifierhttp://dx.doi.org/10.1016/j.vibspec.2022.103489
dc.identifier.citationVibrational Spectroscopy, v. 124.
dc.identifier.doi10.1016/j.vibspec.2022.103489
dc.identifier.issn0924-2031
dc.identifier.scopus2-s2.0-85144824666
dc.identifier.urihttp://hdl.handle.net/11449/249507
dc.language.isoeng
dc.relation.ispartofVibrational Spectroscopy
dc.sourceScopus
dc.subjectBone tissue
dc.subjectMinerals
dc.subjectPhysical training
dc.subjectRaman Spectroscopy
dc.subjectSomatropin
dc.titleEffects of resistance exercise training on bone physical and mineral properties in rats submitted to growth hormone interventionen
dc.typeArtigo
unesp.departmentFísica, Química e Biologia - FCTpt

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