Reliability of carnitine concentrations measured in single postprandial urine samples from dogs
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1996-08-01
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Objective - To evaluate the reliability of urine carnitine concentrations measured in single postprandial samples, compared with carnitine concentrations measured in 24-hour urine samples. Animals - 19 healthy Beagles. Procedure - After emptying the urinary bladder by catheterization, dogs were fed a canned canine maintenance diet. Approximately 8 hours later, urine, plasma, and serum samples were obtained for determination of urinary carnitine fractional excretion and urine carnitine-to-creatinine concentration ratio. Results were compared with 24-hour urinary carnitine excretion rate. Results - Fractional excretion of carnitine and urine carnitine-to-creatinine ratios correlated poorly with 24-hour urinary carnitine excretion. Conclusion - Determination of 24-hour urinary carnitine excretion is recommended to measure urine carnitine concentrations in dogs.
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biological marker , carnitine , animal , animal food , blood , comparative study , dog , female , male , orchiectomy , ovariectomy , postprandial state , reference value , reproducibility , urine , Animal Nutrition Physiology , Animals , Biological Markers , Carnitine , Dogs , Female , Male , Orchiectomy , Ovariectomy , Postprandial Period , Reference Values , Reproducibility of Results
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American Journal of Veterinary Research, v. 57, n. 8, p. 1185-1188, 1996.