Distúrbios neurológicos em trabalhadores com baixos níveis de chumbo no sangue. I: Neuropatia periférica

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Cordeiro, Ricardo [UNESP]
Lima Filho, Euclydes C.
Salgado, Paulo E. T.

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This is a cross-sectional study with a randomized choice of individuals aiming at studying the validity of the Brazilian biological exposure limits applied to lead level in the blood (PbB) and delta-aminolevulinic acid in the urine (ALAU), which are 60 μg/dl and 10 mg/g.creat., respectively. For this purpose, twenty workers, whose PbB and ALAU values have been below these limits over the past two years, were selected at random at a battery production plant in the State of S. Paulo, Brazil. The workers were submitted to a peripheral nerve conduction study. The results were compared with those obtained for workers of a control group also chosen at random. The lead workers showed a decrease in the velocity conduction of the radial nerves. Comparing this group with a randomized control group, a significant difference was observed (p-value = 0.0067). The results suggest that the Brazilian biological exposure limits above should be rearranged.



Lead poisoning, prevention, Occupational exposure, standard, Peripheral nervous system diseases, chemical induced, adult, blood, case control study, chemically induced disorder, clinical trial, controlled clinical trial, controlled study, human, lead poisoning, male, maximum allowable concentration, nerve conduction, occupational disease, pathophysiology, peripheral neuropathy, randomized controlled trial, Adult, Case-Control Studies, Humans, Lead Poisoning, Male, Maximum Allowable Concentration, Neural Conduction, Occupational Diseases, Peripheral Nervous System Diseases

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Revista de Saude Publica, v. 30, n. 3, p. 248-255, 1996.