Analytical Methods for the Determination of Rosuvastatin in Pharmaceutical Formulations and Biological Fluids: A Critical Review

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dc.contributor.authorÂngelo, Marilene Lopes
dc.contributor.authorMoreira, Fernanda de Lima
dc.contributor.authorMorais Ruela, André Luís
dc.contributor.authorSantos, Ana Laura Araújo
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.authorde Araújo, Magali Benjamim
dc.contributor.institutionFederal University of Alfenas
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal da Bahia (UFBA)
dc.contributor.institutionBangor University
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:36:18Z
dc.date.available2018-12-11T17:36:18Z
dc.date.issued2018-07-04
dc.description.abstractRosuvastatin calcium (ROS), (Figure 1) belongs to the “statins” group, which is the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. This drug is indicated for dyslipidemias treatment and can help to decrease the level of “bad cholesterol” and can consequently reduce the development of atherosclerosis and the risk of heart diseases. ROS was developed by Astra-Zeneca and it was approved in 2003 by the FDA in the United States. In 2015, under the trade name Crestor®, it was the fourth largest selling drug in the United States with sales above $5 billion. This study presents a literature review of analytical methods for the quantification of ROS in pharmaceutical preparations and biological fluids. The major analytical methods described in this study for ROS were spectrophotometry, high-performance liquid chromatography (HPLC) coupled to ultraviolet (UV) detection, and tandem mass spectrometry (LC–MS/MS).en
dc.description.affiliationFaculty of Pharmaceutical Sciences Federal University of Alfenas
dc.description.affiliationSchool of Pharmaceutical Sciences of Ribeirão Preto São Paulo University
dc.description.affiliationMultidisciplinary Health Institute Federal University of Bahia
dc.description.affiliationSchool of Biological Sciences Bangor University
dc.description.affiliationFaculty of Pharmaceutical Sciences UNESP
dc.description.affiliationUnespFaculty of Pharmaceutical Sciences UNESP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 016/23938-2
dc.format.extent317-329
dc.identifierhttp://dx.doi.org/10.1080/10408347.2018.1439364
dc.identifier.citationCritical Reviews in Analytical Chemistry, v. 48, n. 4, p. 317-329, 2018.
dc.identifier.doi10.1080/10408347.2018.1439364
dc.identifier.file2-s2.0-85043704767.pdf
dc.identifier.issn1547-6510
dc.identifier.issn1040-8347
dc.identifier.scopus2-s2.0-85043704767
dc.identifier.urihttp://hdl.handle.net/11449/179673
dc.language.isoeng
dc.relation.ispartofCritical Reviews in Analytical Chemistry
dc.relation.ispartofsjr0,819
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAnalytical methods
dc.subjectHPLC
dc.subjectLC–MS/MS
dc.subjectrosuvastatin
dc.subjectspectrophotometry
dc.titleAnalytical Methods for the Determination of Rosuvastatin in Pharmaceutical Formulations and Biological Fluids: A Critical Reviewen
dc.typeResenha
unesp.author.orcid0000-0003-1258-8705[3]
unesp.author.orcid0000-0002-0385-340X[5]
unesp.author.orcid0000-0002-3564-4338[6]
unesp.departmentFármacos e Medicamentos - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas