In situ evaluation of the remineralizing capacity of pit and fissure sealants containing amorphous calcium phosphate and/or fluoride

dc.contributor.authorSilva, Kelio Garcia [UNESP]
dc.contributor.authorPedrini, Denise [UNESP]
dc.contributor.authorDelbem, Alberto Carlos Botazzo [UNESP]
dc.contributor.authorFerreira, Lilian [UNESP]
dc.contributor.authorCannon, Mark
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionNorthwestern University (NU)
dc.date.accessioned2013-09-30T18:30:36Z
dc.date.accessioned2014-05-20T13:43:11Z
dc.date.available2013-09-30T18:30:36Z
dc.date.available2014-05-20T13:43:11Z
dc.date.issued2010-01-01
dc.description.abstractObjective. This in situ study evaluated the remineralizing potential of pit and fissure sealants containing amorphous calcium phosphate (ACP) and/or fluoride in artificially induced carious lesions on smooth enamel surfaces. Material and methods. Ten volunteers who wore acrylic palatal devices were enrolled in this 5-day double-blind study and assigned to one of the following five groups: (I) demineralized enamel slab+Fluroshield (sealant with fluoride); (11) demineralized enamel slab+Aegis (sealant with ACP); (III) demineralized enamel slab+experimental sealant with fluoride (ESF); (IV) demineralized enamel slab +experimental sealant with fluoride/ACP (ACP-F); and (V) demineralized enamel slab (control). After the experimental period, the percentage of surface microhardness recovery(%SMHR) and the integrated loss of subsurface hardness (Delta KHN) were evaluated. The concentrations of fluoride, calcium and phosphorus in enamel were also determined. Results. The sealants containing ACP and/or fluoride presented a higher remineralizing capacity (%SMHR and Delta KHN) than that of the control group. Aegis provided either more efficient or similar remineralization than the other sealants. The association between ACP and fluoride did not show a greater efficacy in the remineralization. F, Ca and P concentrations in enamel varied according to the group. Conclusion. The pit and fissure sealants containing ACP were able to promote remineralization of artificially induced carious lesions on smooth enamel surfaces.en
dc.description.affiliationSão Paulo State Univ, Aracatuba Dent Sch, Post Graduat Program Pediat Dent, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, Aracatuba Dent Sch, Dept Surg, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, Aracatuba Dent Sch, Integrated Clin, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, Aracatuba Dent Sch, Dept Child & Social Dent, São Paulo, Brazil
dc.description.affiliationNorthwestern Univ, Childrens Mem Hosp, Chicago, IL 60614 USA
dc.description.affiliationUnespSão Paulo State Univ, Aracatuba Dent Sch, Post Graduat Program Pediat Dent, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Aracatuba Dent Sch, Dept Surg, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Aracatuba Dent Sch, Integrated Clin, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Aracatuba Dent Sch, Dept Child & Social Dent, São Paulo, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent11-18
dc.identifierhttp://dx.doi.org/10.3109/00016350903260264
dc.identifier.citationActa Odontologica Scandinavica. Oslo: Taylor & Francis As, v. 68, n. 1, p. 11-18, 2010.
dc.identifier.doi10.3109/00016350903260264
dc.identifier.issn0001-6357
dc.identifier.orcid0000-0002-8159-4853
dc.identifier.urihttp://hdl.handle.net/11449/15040
dc.identifier.wosWOS:000274406500002
dc.language.isoeng
dc.publisherTaylor & Francis As
dc.relation.ispartofActa Odontologica Scandinavica
dc.relation.ispartofjcr1.522
dc.relation.ispartofsjr0,706
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectCalcium phosphatesen
dc.subjectfluoridesen
dc.subjectpit and fissure sealantsen
dc.subjecttooth remineralizationen
dc.titleIn situ evaluation of the remineralizing capacity of pit and fissure sealants containing amorphous calcium phosphate and/or fluorideen
dc.typeArtigo
dcterms.licensehttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf
dcterms.rightsHolderTaylor & Francis As
unesp.author.lattes0421571920582994[3]
unesp.author.orcid0000-0002-8159-4853[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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