Aditivos de formulação na formação de filmes isolados de etilcelulose. estudos físico-químicos e morfológicos

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Alves, Bruno R. V.
Reis, Andre L.
Hechenleitner, Ana A. W.
Pineda, Edgardo A. G.
Job, Aldo Eloizo [UNESP]
Cavalcanti, Osvaldo A.
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Colegio Farmaceuticos Provincia de Buenos Aires
Formulation Additives on Formation of Films isolated from Ethylcellulose. Physicochemical and Morphological Studies. In this work were developed free films from Surelease (R), additives alpha-GOS (alfa-glucooligosaccharide) and/or Tween (R) 80 in aqueous solution. It was obtained by Teflon plates casting process. The free films were characterized by thermal analysis (DSC and TGA), infrared spectroscopy (FTIR-ATR) and scanning electron microscopy (SEM). DSC and TO analysis showed that the additives do not influenced in the thermal stability of Surelease (R) films. SEM analysis observed homogeneous morphological characteristics and phase detachment absence. FTIR-ATR spectra were used to confirm the physical mixture between the components of films.
Surelease (R), Free films, alpha-glucooligosaccharide, Prebiotics
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Latin American Journal of Pharmacy. La Plata: Colegio Farmaceuticos Provincia de Buenos Aires, v. 28, n. 6, p. 885-891, 2009.