Post-partum depression: From clinical understanding to preclinical assessments

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dc.contributor.authorMoreira, Lorrane K. S.
dc.contributor.authorMoreira, Caroline V. L.
dc.contributor.authorCustódio, Carlos H. X.
dc.contributor.authorDias, Matheus L. P.
dc.contributor.authorRosa, Daniel A.
dc.contributor.authorFerreira-Neto, Marcos L.
dc.contributor.authorColombari, Eduardo [UNESP]
dc.contributor.authorCosta, Elson A.
dc.contributor.authorFajemiroye, James O.
dc.contributor.authorPedrino, Gustavo R.
dc.contributor.institutionUniversidade Federal de Goiás (UFG)
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionEvangelical University of Goiás
dc.date.accessioned2023-07-29T16:14:13Z
dc.date.available2023-07-29T16:14:13Z
dc.date.issued2023-01-01
dc.description.abstractPost-partum depression (PPD) with varying clinical manifestations affecting new parents remains underdiagnosed and poorly treated. This minireview revisits the pharmacotherapy, and relevant etiological basis, capable of advancing preclinical research frameworks. Maternal tasks accompanied by numerous behavioral readouts demand modeling different paradigms that reflect the complex and heterogenous nature of PPD. Hence, effective PPD-like characterization in animals towards the discovery of pharmacological intervention demands research that deepens our understanding of the roles of hormonal and non-hormonal components and mediators of this psychiatric disorder.en
dc.description.affiliationInstitute of Biological Sciences Federal University of Goiás, GO
dc.description.affiliationDepartment of Physiology Institute of Biomedical Sciences Federal University of Uberlândia
dc.description.affiliationDepartment of Physiology and Pathology School of Dentistry São Paulo State University (UNESP)
dc.description.affiliationGraduate Program in Pharmaceutical Sciences Evangelical University of Goiás, Campus Arthur Wesley Archibald
dc.description.affiliationUnespDepartment of Physiology and Pathology School of Dentistry São Paulo State University (UNESP)
dc.identifierhttp://dx.doi.org/10.3389/fpsyt.2023.1173635
dc.identifier.citationFrontiers in Psychiatry, v. 14.
dc.identifier.doi10.3389/fpsyt.2023.1173635
dc.identifier.issn1664-0640
dc.identifier.scopus2-s2.0-85159902130
dc.identifier.urihttp://hdl.handle.net/11449/249969
dc.language.isoeng
dc.relation.ispartofFrontiers in Psychiatry
dc.sourceScopus
dc.subjectbehavioral models
dc.subjectdepression
dc.subjectpharmacological targets
dc.subjectpost-partum
dc.subjectpreclinical assessments
dc.titlePost-partum depression: From clinical understanding to preclinical assessmentsen
dc.typeArtigo

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