Técnicas de Neurorrafia: Estudio Experimental Estereológico Axonal Comparativo

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dc.contributor.authorBoer, Nagib Pezati
dc.contributor.authorBatigalia, Fernando
dc.contributor.authorViterbo, Fausto [UNESP]
dc.contributor.authorFaleiros, Humberto Regis de Paula
dc.contributor.authorRamos, Rogério Rodrigo
dc.contributor.authorSimonato, Luciana Estevam
dc.contributor.authorBoer, Luis Fernando Ricci
dc.contributor.institutionUniversity Camilo Castelo Branco, UCCB and Foundation Education of Fernandópolis, FEF - Fernandópolis
dc.contributor.institutionSão José do Rio Preto Medical School, FAMERP
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCamilo Castelo Branco University
dc.contributor.institutionUniversity Camilo Castelo Branco and Education Foundation of Fernandópolis
dc.contributor.institutionCamilo Castelo Branco University, and Education Foundation of Fernandópolis
dc.contributor.institutionAnhembi Morumbi University
dc.date.accessioned2018-12-11T17:25:51Z
dc.date.available2018-12-11T17:25:51Z
dc.date.issued2015-01-01
dc.description.abstractThere is a great variety of injuries that affect peripheral nerves derived from acquired or congenital degenerative diseases affecting the central nervous system that cause loss of sensorimotor functions. The objective of this work was to perform an endto- side or side-to-side experimental axonal stereological study in order to compare volume density of axons, endouneuro and myelin sheath (and muscle mass) in peroneal and tibial nerves, with anastomosis contact from 0.25 cm to 0.50 cm. After approval of the Ethics Committe, 20 male Wistar rats were divided into four groups of five rats each (G1= end-to-side neurorrhaphy; G2= side-to-side neurorrhaphy of 0.25 cm; G3= side-to-side neurorrhaphy of 0 cm and G4= Control of normality). After 180 days, fragments of peroneal and tibial nerves were collected for histological and stereological study. In comparative stereological experimental study between neurorraphies, the volume density of axons, myelin sheath of tibial and fibular nerves, as well as the post-surgical muscle mass, remains the same in end-to-side and side-to-side neurorraphies, regardless of contact area of anastomosis. It can be inferred, as surgical repair options, both end-to-side neurorrhaphy to recover and prevents atrophy of the endplate as side-to-side neurorraphy that is independent of the distance between the nerve stumps.en
dc.description.affiliationUniversity Camilo Castelo Branco, UCCB and Foundation Education of Fernandópolis, FEF - Fernandópolis
dc.description.affiliationSão José do Rio Preto Medical School, FAMERP
dc.description.affiliationState University of São Paulo, Unesp- Botucatu
dc.description.affiliationCamilo Castelo Branco University
dc.description.affiliationUniversity Camilo Castelo Branco and Education Foundation of Fernandópolis
dc.description.affiliationCamilo Castelo Branco University, and Education Foundation of Fernandópolis
dc.description.affiliationAnhembi Morumbi University
dc.description.affiliationUnespState University of São Paulo, Unesp- Botucatu
dc.format.extent1002-1008
dc.identifierhttp://dx.doi.org/10.4067/S0717-95022015000300031
dc.identifier.citationInternational Journal of Morphology, v. 33, n. 3, p. 1002-1008, 2015.
dc.identifier.doi10.4067/S0717-95022015000300031
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.scopus2-s2.0-84943389510
dc.identifier.urihttp://hdl.handle.net/11449/177526
dc.language.isoeng
dc.relation.ispartofInternational Journal of Morphology
dc.relation.ispartofsjr0,207
dc.relation.ispartofsjr0,207
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAxon
dc.subjectEndoneurium
dc.subjectMyelin sheath
dc.subjectNeurorraphy
dc.subjectReinnervation
dc.subjectStereolog0y
dc.titleTécnicas de Neurorrafia: Estudio Experimental Estereológico Axonal Comparativoes
dc.title.alternativeNeurorrhaphy techniques: Comparative stereological and experimental axonal studyen
dc.typeArtigo

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Artigos - Cirurgia e Ortopedia - FMB