Publicação:
KSHV genotypes A and C are more frequent in Kaposi sarcoma lesions from Brazilian patients with and without HIV infection, respectively

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dc.contributor.authorSilva, Suzane Ramos de [UNESP]
dc.contributor.authorSilva, Ana Paula Ferraz da [UNESP]
dc.contributor.authorBacchi, Maura Moscardi [UNESP]
dc.contributor.authorBacchi, Carlos Eduardo [UNESP]
dc.contributor.authorOliveira, Deilson Elgui de [UNESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:37:37Z
dc.date.available2014-05-20T13:37:37Z
dc.date.issued2011-02-01
dc.description.abstractThe present study aimed to evaluate the frequency of KSHV genotypes isolated from Kaposi sarcoma (KS) lesions in patients from Brazil. Fifty KS cases were evaluated. The most frequently detected viral genotypes were A (50.0%) and C (48.0%); the B genotype was isolated only in one case (2.0%). Noteworthy, there was a significant predominance of A genotypes in KS lesions from HIV-positive patients, whereas C genotypes were found mostly in the HIV-negative setting. This finding supports the hypothesis that distinct KSHV genotypes have a non-random distribution in KS, which might be attributable to unique biological properties. (C) 2010 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniv São Paulo, Botucatu Med Sch, Dept Pathol, BR-05508 São Paulo, Brazil
dc.description.affiliationConsultoria Patol, São Paulo, Brazil
dc.description.affiliationUnespUniv São Paulo, Botucatu Med Sch, Dept Pathol, BR-05508 São Paulo, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdFAPESP: 04/10907-5
dc.description.sponsorshipIdFAPESP: 06/50018-0
dc.format.extent85-94
dc.identifierhttp://dx.doi.org/10.1016/j.canlet.2010.10.011
dc.identifier.citationCancer Letters. Clare: Elsevier B.V., v. 301, n. 1, p. 85-94, 2011.
dc.identifier.doi10.1016/j.canlet.2010.10.011
dc.identifier.issn0304-3835
dc.identifier.lattes5240998569868081
dc.identifier.urihttp://hdl.handle.net/11449/13043
dc.identifier.wosWOS:000287108900010
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofCancer Letters
dc.relation.ispartofjcr6.491
dc.relation.ispartofsjr2,350
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectKSHVen
dc.subjectHHV-8en
dc.subjectKaposi sarcomaen
dc.subjectViral genotypingen
dc.titleKSHV genotypes A and C are more frequent in Kaposi sarcoma lesions from Brazilian patients with and without HIV infection, respectivelyen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.author.lattes5240998569868081
unesp.author.orcid0000-0001-5562-9648[5]
unesp.author.orcid0000-0002-0768-8421[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentPatologia - FMBpt

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Botucatu - FMB - Faculdade de Medicina