Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas

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dc.contributor.authorDe Nardi, A. B. [UNESP]
dc.contributor.authorDaleck, C. R. [UNESP]
dc.contributor.authorAmorin, R. L. [UNESP]
dc.contributor.authorHuppes, R. R. [UNESP]
dc.contributor.authorUscategui, R. A. R. [UNESP]
dc.contributor.authorRodaski, S.
dc.contributor.authorCalderon, C.
dc.contributor.authorNeto, R. T. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Paraná (UFPR)
dc.contributor.institutionUniv Estadual Norte Parana
dc.date.accessioned2014-12-03T13:07:05Z
dc.date.available2014-12-03T13:07:05Z
dc.date.issued2013-01-01
dc.description.abstractThe aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P < 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.en
dc.description.affiliationUniv Estadual Paulista, Dept Clin & Cirugia Vet, Sao Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Dept Clin Vet, Sao Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Programa Clin Vet, Sao Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Programa Cirugia Vet, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Parana, Dept Vet Med, BR-80060000 Curitiba, Parana, Brazil
dc.description.affiliationUniv Estadual Norte Parana, Bandeirantes, Parana, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Clin & Cirugia Vet, Sao Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Clin Vet, Sao Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Programa Clin Vet, Sao Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Programa Cirugia Vet, Sao Paulo, Brazil
dc.format.extent311-316
dc.identifierhttp://dx.doi.org/10.4067/S0301-732X2013000300012
dc.identifier.citationArchivos De Medicina Veterinaria. Valdivia: Univ Austral Chile, Fac Ciencias Veterinarias, v. 45, n. 3, p. 311-316, 2013.
dc.identifier.doi10.4067/S0301-732X2013000300012
dc.identifier.fileWOS000330203700011.pdf
dc.identifier.issn0301-732X
dc.identifier.urihttp://hdl.handle.net/11449/111230
dc.identifier.wosWOS:000330203700011
dc.language.isospa
dc.publisherUniv Austral Chile, Fac Ciencias Veterinarias
dc.relation.ispartofArchivos de Medicina Veterinária
dc.relation.ispartofjcr0.236
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectCanceren
dc.subjectMammary neoplasmen
dc.subjectciclooxigenase-2en
dc.subjectDogen
dc.titleCyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomasen
dc.typeArtigo
dcterms.rightsHolderUniv Austral Chile, Fac Ciencias Veterinarias
unesp.author.lattes5256503293611165[1]
unesp.author.orcid0000-0001-6463-2144[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

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Artigos - Clínica e Cirurgia Veterinária - FCAV