Minimum Evaporation Model of Dermatological Delivery Systems. Lamellar Liquid Crystal Formulations Containing Brazilian Nut (Bertholletia excelsa HBK) Vegetable Oil and Guarana Glycolic Extract

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dc.contributor.authorMonteiro e Silva, Silas Arandas
dc.contributor.authorCosta Valarini, Michele Fernanda
dc.contributor.authorChorilli, Marlus [UNESP]
dc.contributor.authorFriberg, Stig E.
dc.contributor.authorLeonardi, Gislaine Ricci
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Metodista Piracicaba
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionNTNU
dc.date.accessioned2014-12-03T13:09:13Z
dc.date.available2014-12-03T13:09:13Z
dc.date.issued2014-01-01
dc.description.abstractFormulations with lyotropic liquid crystals were prepared from a Brazilian nut vegetable oil, guarana extract and combination of sorbitan monooleate (Span 80) and sorbitan monolaurate ethoxylate EO 20 (Tween 20) in the ratio 1: 3 (surfactant component) and their physical-chemical aspects and rheological properties were determined. Compositions with liquid crystals were found in the pseudoternary diagram in a surfactant range of 70-90% and polarized light microscopy, small-angle x-ray scattering (SAXS) showed them to be lamellar. The preparations were furthermore characterized rheologically by shear stress shear rate sweeps finding plastic and pseudoplastic behavior without thixotropy. Electric conductivity and pH measurements demonstrated a potential for future application as dermatological delivery system of the active compounds in the Bertholletia excelsa and Paullinia cupana.en
dc.description.affiliationUniv Fed Sao Paulo, UNIFESP, Dept Med, Sao Paulo, Brazil
dc.description.affiliationUniv Metodista Piracicaba, UNIMEP, Pharm Course, Piracicaba, Brazil
dc.description.affiliationSao Paulo State Univ, UNESP, Sch Pharmaceut Sci, Araraquara, Brazil
dc.description.affiliationNTNU, Ugelstad Lab, Trondheim, Norway
dc.description.affiliationUniv Fed Sao Paulo, UNIFESP, Inst Environm Chem & Pharmaceut Sci, Diadema, Brazil
dc.description.affiliationUnespSao Paulo State Univ, UNESP, Sch Pharmaceut Sci, Araraquara, Brazil
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent1191-1199
dc.identifierhttp://dx.doi.org/10.1080/01932691.2013.826586
dc.identifier.citationJournal Of Dispersion Science And Technology. Philadelphia: Taylor & Francis Inc, v. 35, n. 8, p. 1191-1199, 2014.
dc.identifier.doi10.1080/01932691.2013.826586
dc.identifier.issn0193-2691
dc.identifier.urihttp://hdl.handle.net/11449/112077
dc.identifier.wosWOS:000337632100016
dc.language.isoeng
dc.publisherTaylor & Francis Inc
dc.relation.ispartofJournal of Dispersion Science and Technology
dc.relation.ispartofjcr1.454
dc.relation.ispartofsjr0,375
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectCosmeticsen
dc.subjectdermatological formulationsen
dc.subjectliquid crystalsen
dc.subjectrheologyen
dc.subjectvegetable oilsen
dc.titleMinimum Evaporation Model of Dermatological Delivery Systems. Lamellar Liquid Crystal Formulations Containing Brazilian Nut (Bertholletia excelsa HBK) Vegetable Oil and Guarana Glycolic Extracten
dc.typeArtigo
dcterms.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dcterms.rightsHolderTaylor & Francis Inc
unesp.author.orcid0000-0002-7126-1326[5]
unesp.author.orcid0000-0002-6698-0545[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas