Comparison between intermittent mandatory ventilation and synchronized intermittent mandatory ventilation with pressure support in children

dc.contributor.authorde Moraes, Marcos A. [UNESP]
dc.contributor.authorBonatto, Rossano César [UNESP]
dc.contributor.authorCarpi, Mario Ferreira [UNESP]
dc.contributor.authorRicchetti, Sandra M. Q. [UNESP]
dc.contributor.authorPadovani, Carlos Roberto [UNESP]
dc.contributor.authorFioretto, José Roberto [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:38:01Z
dc.date.available2014-05-20T13:38:01Z
dc.date.issued2009-01-01
dc.description.abstractObjective: To compare intermittent mandatory ventilation (IMV) with synchronized intermittent mandatory ventilation plus pressure support (SIMV+PS) in terms of time on mechanical ventilation, duration of weaning and length of stay in a pediatric intensive care unit (PICU).Methods: This was a randomized clinical trial that enrolled children aged 28 days to 4 years who were admitted to a PICU between October of 2005 and June of 2007 and put on mechanical ventilation (MV) for more than 48 hours. These patients were allocated to one of two groups by drawing lots: IMV group (IMVG; n = 35) and SIMV+PS group (SIMVG; n = 35). Children were excluded if they had undergone tracheotomy or had chronic respiratory diseases. Data on oxygenation and ventilation were recorded at admission and at the start of weaning.Results: There were no statistical differences between the groups in terms of age, sex, indication for MV, PRISM score, Comfort scale, use of sedatives or ventilation and oxygenation parameters. The median time on MV was 5 days for both groups (p = 0.120). There were also no statistical differences between the two groups for duration of weaning [IMVG: 1 day (1-6) vs. SIMVG: 1 day (1-6); p = 0.262] or length of hospital stay [IMVG: 8 days (2-22) vs. SIMVG: 6 days (3-20); p = 0.113].Conclusion: Among the children studied here, there was no statistically significant difference between IMV and SIMV+ PS in terms of time on MV, duration of weaning or time spent in the PICU.ClinicalTrials.govID: NCT00549809.en
dc.description.affiliationUNESP, Dept Pediat, Fac Med Botucatu, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUNESP, UTI Pediat, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUNESP, Inst Biociencias, Dept Bioestat, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP, Dept Pediat, Fac Med Botucatu, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP, UTI Pediat, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUnespUNESP, Inst Biociencias, Dept Bioestat, BR-18618000 Botucatu, SP, Brazil
dc.format.extent15-20
dc.identifierhttp://dx.doi.org/10.2223/JPED.1849
dc.identifier.citationJornal de Pediatria. Rio de Janeiro, Rj: Soc Brasil Pediatria, v. 85, n. 1, p. 15-20, 2009.
dc.identifier.doi10.2223/JPED.1849
dc.identifier.issn0021-7557
dc.identifier.lattes0246391303241376
dc.identifier.lattes8727897080522289
dc.identifier.lattes3929692206834380
dc.identifier.orcid0000-0002-0648-876X
dc.identifier.urihttp://hdl.handle.net/11449/13185
dc.identifier.wosWOS:000264044200004
dc.language.isoeng
dc.publisherSociedade Brasileira de Pediatria
dc.relation.ispartofJornal de Pediatria
dc.relation.ispartofjcr1.690
dc.relation.ispartofsjr0,704
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleComparison between intermittent mandatory ventilation and synchronized intermittent mandatory ventilation with pressure support in childrenen
dc.typeArtigo
dcterms.rightsHolderSoc Brasil Pediatria
unesp.author.lattes0246391303241376[2]
unesp.author.lattes8727897080522289[5]
unesp.author.lattes3929692206834380
unesp.author.orcid0000-0002-7719-9682[5]
unesp.author.orcid0000-0002-0648-876X[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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