Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products

dc.contributor.authorSoares, Luciana Arantes [UNESP]
dc.contributor.authorSardi, Janaína De Cássia Orlandi [UNESP]
dc.contributor.authorGullo, Fernanda Patrícia [UNESP]
dc.contributor.authorPitangui, Nayla De Souza [UNESP]
dc.contributor.authorScorzoni, Liliana [UNESP]
dc.contributor.authorLeite, Fernanda Sangalli [UNESP]
dc.contributor.authorMendes-Giannini, Maria José Soares [UNESP]
dc.contributor.authorAlmeida, Ana Marisa Fusco [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-10-01T13:08:55Z
dc.date.available2014-10-01T13:08:55Z
dc.date.issued2013-12-01
dc.description.abstractMillions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.en
dc.description.affiliationUniversidade Estadual Paulista Faculdade de Ciências Farmacêuticas Departamento de Análises Clínicas
dc.description.affiliationUnespUniversidade Estadual Paulista Faculdade de Ciências Farmacêuticas Departamento de Análises Clínicas
dc.format.extent1035-1041
dc.identifierhttp://dx.doi.org/10.1590/S1517-83822014005000011
dc.identifier.citationBrazilian Journal of Microbiology. Sociedade Brasileira de Microbiologia, v. 44, n. 4, p. 1035-1041, 2013.
dc.identifier.doi10.1590/S1517-83822014005000011
dc.identifier.fileS1517-83822013000400003.pdf
dc.identifier.issn1517-8382
dc.identifier.orcid0000-0002-8059-0826
dc.identifier.scieloS1517-83822013000400003
dc.identifier.urihttp://hdl.handle.net/11449/110220
dc.identifier.wosWOS:000333959600003
dc.language.isoeng
dc.publisherSociedade Brasileira de Microbiologia
dc.relation.ispartofBrazilian Journal of Microbiology
dc.relation.ispartofjcr1.810
dc.relation.ispartofsjr0,630
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectdermatophytesen
dc.subjectfilamentous fungien
dc.subjectnatural productsen
dc.subjectsynthetic producten
dc.titleAnti dermatophytic therapy: prospects for the discovery of new drugs from natural productsen
dc.typeArtigo
unesp.author.lattes3716273524139678[8]
unesp.author.orcid0000-0002-8059-0826[7]
unesp.author.orcid0000-0002-2115-8988[8]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentAnálises Clínicas - FCFpt

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