Descripción inmunohistoquímica de la encefalitis en bovinos brasileños naturalmente infectados con el herpesvirus bovino tipo 5 (HVB-5)

dc.contributor.authorPedraza, F. J.
dc.contributor.authorSchild, A. L.
dc.contributor.authorAlessi, A. C. [UNESP]
dc.contributor.institutionUniversidad de Caldas
dc.contributor.institutionRS-Universidad Federal de Pelotas
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:23:35Z
dc.date.available2014-05-27T11:23:35Z
dc.date.issued2008-07-01
dc.description.abstractTwelve cases of viral meningoencephalitis in Brazilian cattle were submitted to immunohistochemical analysis for inflammatory response description. All the cases showed severe neurological signs followed by death. Mild to moderate histological inflammatory changes in the brain and cerebellum characterized the neurological infection showing meningitis, mononuclear perivascular cuffing, gliosis, haemorrhage, and macrophages (gitter cells) accompanying great areas of malacia. None of the cases showed intranuclear inclusion bodies. However, in five of them it was possible to isolate the BoHV-5. In order to collect data to allow the description of the inflammatory response in these cases, brain samples from all of the cases were analyzed by immunohistochemistry using polyclonal antibodies against CD3 to detect T cells, and against GFAP to detect astrocytes. On the other hand, monoclonal antibodies were used against BLA to detect B cells and, against MAC 387 to detect macrophages. The results indicate different degrees of prominent astrocytic response, and at the same time, T lymphocytes constituted a high percentage of the mononuclear cells which characterized the inflammatory response.en
dc.description.affiliationGrupo de Patología Veterinaria Departamento de Salud Animal Universidad de Caldas, Manizales
dc.description.affiliationLaboratorio Regional de Diagnóstico Facultad de Veterinaria RS-Universidad Federal de Pelotas
dc.description.affiliationDepartamento de Patología Veterinaria Faculdade de Ciencias Agrarias Y Veterinarias Universidad Estadual Paulista
dc.description.affiliationFCAV Unesp, Via Prof. Paulo Castellane, s/n, Jaboticabal, CEP 14884-900. Sao Paulo
dc.description.affiliationUnespDepartamento de Patología Veterinaria Faculdade de Ciencias Agrarias Y Veterinarias Universidad Estadual Paulista
dc.description.affiliationUnespFCAV Unesp, Via Prof. Paulo Castellane, s/n, Jaboticabal, CEP 14884-900. Sao Paulo
dc.format.extent69-75
dc.identifierhttp://dx.doi.org/10.4067/S0301-732X2008000100010
dc.identifier.citationArchivos de Medicina Veterinaria, v. 40, n. 1, p. 69-75, 2008.
dc.identifier.doi10.4067/S0301-732X2008000100010
dc.identifier.file2-s2.0-45849144430.pdf
dc.identifier.issn0301-732X
dc.identifier.issn0717-6201
dc.identifier.scieloS0301-732X2008000100010
dc.identifier.scopus2-s2.0-45849144430
dc.identifier.urihttp://hdl.handle.net/11449/70462
dc.language.isospa
dc.relation.ispartofArchivos de Medicina Veterinária
dc.relation.ispartofjcr0.236
dc.relation.ispartofsjr0,194
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectBoHV-5
dc.subjectBovine polioencephalomalacia
dc.subjectViral encephalitis
dc.subjectBos
dc.subjectBovinae
dc.subjectBovine herpesvirus 5
dc.subjectHerpesviridae
dc.titleDescripción inmunohistoquímica de la encefalitis en bovinos brasileños naturalmente infectados con el herpesvirus bovino tipo 5 (HVB-5)es
dc.title.alternativeImmunohistochemical description of encephalitis in Brazilian cattle naturally infected with bovine herpes virus type 5 (BoHV-5)en
dc.typeArtigo
dcterms.licensehttp://www.scielo.cl/revistas/amv/eaboutj.htm#Copyright
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt
unesp.departmentPatologia Veterinária - FCAVpt

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