Angioleiomyoma affecting the lips: Report of 3 cases and review of the literature

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dc.contributor.authorGueiros, Luiz-Alcino
dc.contributor.authorRomañach, Mário-José
dc.contributor.authorPires-Soubhia, Ana-Maria
dc.contributor.authorPires, Fábio-Ramôa
dc.contributor.authorPaes-de-Almeida, Oslei
dc.contributor.authorVargas, Pablo-Agustin
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionJúlio Mesquista State University
dc.contributor.institutionEstácio de Sá University
dc.date.accessioned2022-04-29T08:44:25Z
dc.date.available2022-04-29T08:44:25Z
dc.date.issued2011-07-01
dc.description.abstractAngioleiomyoma is an uncommon benign soft tissue tumor usually found in the lower extremities and rarely observed in oral tissues. It is microscopically characterized as a proliferation of smooth muscle cells intermingled with abundant vascular channels. Oral angioleiomyomas affect mostly the lips, palate, buccal mucosa and tongue, and appears as a submucosal painless nodule. Upper lip is seldom affected and only few cases have been reported. We report three additional cases of angioleiomyoma affecting the lips of elderly patients. All lesions were asymptomatic and presented as submucosal nodules of approximately 1cm. Microscopic analysis on H&E sections revealed similar pattern in all cases, showing well-circumscribed and encapsulated tumors characterized by proliferation of smooth muscle cells and large amount of wide vascular spaces of varying sizes. Most tumor cells were immunoreactive for α-smooth muscle actin, desmin and HHF-35. CD34 was also positive on the endothelial cells. All patients were surgically treated and no recurrence was observed so far. The oral pathologists and clinicians should consider this entity when assessing nodular lesions on upper lip. © Medicina Oral S. L.en
dc.description.affiliationDepartment of Oral Diagnosis, Laboratory of Oral Pathology Piracicaba Dental School University of Campinas
dc.description.affiliationDepartment of Pathology and Clinical Propedeutics, Laboratory of Oral Pathology Araçatuba Dental School Júlio Mesquista State University
dc.description.affiliationEstácio de Sá University
dc.identifierhttp://dx.doi.org/10.4317/medoral.16.e482
dc.identifier.citationMedicina Oral, Patologia Oral y Cirugia Bucal, v. 16, n. 4, 2011.
dc.identifier.doi10.4317/medoral.16.e482
dc.identifier.issn1698-4447
dc.identifier.issn1698-6946
dc.identifier.scopus2-s2.0-79960305189
dc.identifier.urihttp://hdl.handle.net/11449/231264
dc.language.isoeng
dc.relation.ispartofMedicina Oral, Patologia Oral y Cirugia Bucal
dc.sourceScopus
dc.subjectAngioleiomyoma
dc.subjectLip neoplasms
dc.subjectVascular neoplasms
dc.titleAngioleiomyoma affecting the lips: Report of 3 cases and review of the literatureen
dc.typeResenha

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Artigos - Patologia e Propedêutica Clínica - FOA