Serum protein concentrations of cattle withnatural fasciola hepatica and strongylids infections

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dc.contributor.authorSchmidt, Elizabeth Moreira dos Santos [UNESP]
dc.contributor.authorThomazini, Camila Martos [UNESP]
dc.contributor.authorMoraes, Lívia Fagundes [UNESP]
dc.contributor.authorDias, Rafael Grobério Souto [UNESP]
dc.contributor.authorReis, Rafael de Oliveira [UNESP]
dc.contributor.authorTakahira, Regina Kiomi [UNESP]
dc.contributor.authorLopes, Raimundo Souza [UNESP]
dc.contributor.authorFagliari, José Jurandir [UNESP]
dc.contributor.authorSilva, Paulo César da [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-07-07T12:34:24Z
dc.date.available2016-07-07T12:34:24Z
dc.date.issued2011
dc.description.abstractAcute phase proteins (APPs) are considered sensitive markers ofinflammation especially in large animals. In this study we deter-mined the profile of acute phase proteins in parasitic diseases using22 Nellore cattle. They were naturally infected with Fasciola hepat-ica and strongylids, which included 70% Cooperia sp., 22%Oesophagostomum sp., 7% Haemonchus sp. and 1% Trichostrongylus sp. by egg count per gram and coprocultures. Serum concentra-tions of acute phase proteins were determined by means of sodiumdodecyl sulphate-polycrylamide gel electrophoresis. Increaseswere observed in concentrations of IgG 4,083  1,034 mg/dL(maximum of 6,765 mg/dL), ceruloplasmin 78.9  22.7 mg/dL(maximum of 119.7 mg/dL – 10 times fold), transferrin 361 114.4 mg/dL, haptoglobin 22.8  14.8 mg/dL (maximum of66.7 mg/dL – 3 times fold), and a1-acid glycoprotein 11.3 5.7 mg/dL (maximum of 24.1 – 2 times fold). The liver enzymesAST and GGT were also increased at 132.2  33 UI/L (maximum of199.5 UI/L) and 282.8  156.6 UI/L (maximum of 650 UI/L). Se-rum total protein, IgA, albumin, and non-nominal identified pro-tein of 23 kD were not significantly increased (P 4 0.05). Theincreases in serum AST, GGT, and the acute phase proteins (cer-uloplasmin, haptoglobin, a1-acid glycoprotein, and specially IgG)demonstrate acute hepatic inflammation mainly caused by Fasciolahepatica. Otherwise, the other parasites may also contribute to thechanges in the acute phase protein concentrations.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinária e Zootecnia (FMVZ), Departamento de Clínica Veterinária, Botucatu, SP, Brasil
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Agrárias e Veterinárias (FCAV), Departamento de Clínica e Cirurgia Veterinária, Jaboticabal, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinária e Zootecnia (FMVZ), Departamento de Clínica Veterinária, Botucatu, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Agrárias e Veterinárias (FCAV), Departamento de Clínica e Cirurgia Veterinária, Jaboticabal, SP, Brasil
dc.format.extent585-586
dc.identifierhttp://dx.doi.org/10.1111/j.1939-165X.2011.00348.x
dc.identifier.citationVeterinary Clinical Pathology, v. 41, n. 1, p. 585-586, 2011.
dc.identifier.doi10.1111/j.1939-165X.2011.00348.x
dc.identifier.issn0275-6382
dc.identifier.lattes2899895473321703
dc.identifier.lattes3517825410178813
dc.identifier.lattes9290459261474398
dc.identifier.orcid0000-0003-3323-4199
dc.identifier.orcid0000-0001-5898-2914
dc.identifier.urihttp://hdl.handle.net/11449/140555
dc.language.isoeng
dc.relation.ispartofVeterinary Clinical Pathology
dc.relation.ispartofjcr0.937
dc.relation.ispartofsjr0,647
dc.rights.accessRightsAcesso restrito
dc.sourceCurrículo Lattes
dc.titleSerum protein concentrations of cattle withnatural fasciola hepatica and strongylids infectionsen
dc.typeArtigo
unesp.author.lattes2899895473321703
unesp.author.lattes3517825410178813
unesp.author.lattes9290459261474398[9]
unesp.author.orcid0000-0003-3323-4199[6]
unesp.author.orcid0000-0001-8297-6979[1]
unesp.author.orcid0000-0001-5898-2914[9]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt
unesp.departmentClínica Veterináriapt
unesp.departmentClínica e Cirurgia Veterinária - FCAVpt

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Artigos - Clínica Veterinária - FMVZ
Jaboticabal - FCAV - Faculdade de Ciências Agrárias e Veterinárias