Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
| dc.contributor.author | Serna‐garcía, Marta [UNESP] | |
| dc.contributor.author | Peiró, Rosa | |
| dc.contributor.author | Serna, Eva | |
| dc.contributor.author | Santacreu, María Antonia | |
| dc.contributor.institution | Universitat Politècnica de València | |
| dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
| dc.contributor.institution | University of Valencia | |
| dc.date.accessioned | 2021-06-25T10:14:03Z | |
| dc.date.available | 2021-06-25T10:14:03Z | |
| dc.date.issued | 2020-10-01 | |
| dc.description.abstract | Litter size is an essential trait in rabbit meat production but with low heritability. A selection experiment for ovulation rate has been performed for 10 generations to improve litter size in rabbits. The selected line increased two ova more than the control line but nevertheless a negative correlation was observed with prenatal survival. A transcriptomic study was performed, using microarrays, in ovarian tissue from females belonging to the selected line and the control line. Our results showed 1357 differential expressed genes and nineteen potential biomarkers associated with prenatal mortality, which could explain differences between litter size in rabbits. Cell death was the most relevant process. | en |
| dc.description.affiliation | Instituto de Ciencia y Tecnología Animal Universitat Politècnica de València | |
| dc.description.affiliation | Faculty of Agricultural and Veterinary Sciences São Paulo State University FCAV/UNESP | |
| dc.description.affiliation | Instituto de Conservación y Mejora de la Agrodiversidad Valenciana Universitat Politècnica de València | |
| dc.description.affiliation | Department of Physiology Faculty of Medicine University of Valencia | |
| dc.description.affiliationUnesp | Faculty of Agricultural and Veterinary Sciences São Paulo State University FCAV/UNESP | |
| dc.description.sponsorship | Generalitat Valenciana | |
| dc.description.sponsorship | Ministério da Educação e Ciência | |
| dc.description.sponsorshipId | Generalitat Valenciana: 2009/125 | |
| dc.description.sponsorshipId | Ministério da Educação e Ciência: AGL2014‐55921‐C2‐1‐P | |
| dc.format.extent | 1-12 | |
| dc.identifier | http://dx.doi.org/10.3390/ani10101924 | |
| dc.identifier.citation | Animals, v. 10, n. 10, p. 1-12, 2020. | |
| dc.identifier.doi | 10.3390/ani10101924 | |
| dc.identifier.issn | 2076-2615 | |
| dc.identifier.scopus | 2-s2.0-85093663113 | |
| dc.identifier.uri | http://hdl.handle.net/11449/205361 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Animals | |
| dc.source | Scopus | |
| dc.subject | Litter size | |
| dc.subject | Ovarian tissue | |
| dc.subject | Ovulation rate | |
| dc.subject | Rabbit | |
| dc.subject | Transcriptomic analysis | |
| dc.title | Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits | en |
| dc.type | Artigo |