Effect of membrane moiety and magnesium ions on the inhibition of matrix-induced alkaline phosphatase by zinc ions
| dc.contributor.author | Clancaglini, Pletro | |
| dc.contributor.author | Plzauro, João M. [UNESP] | |
| dc.contributor.author | Curti, Carlos | |
| dc.contributor.author | Tedesco, Antonio C. | |
| dc.contributor.author | Leone, Francisco A. | |
| dc.contributor.institution | Universidade de São Paulo (USP) | |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
| dc.date.accessioned | 2022-04-28T19:53:48Z | |
| dc.date.available | 2022-04-28T19:53:48Z | |
| dc.date.issued | 1990-01-01 | |
| dc.description.abstract | 1. 1. The inhibition of matrix-induced alkaline phosphatase by zinc ions is due to the displacement of magnesium ions from its binding site. 2. 2. Binding of magnesium ions to alkaline phosphatase induces conformational changes which activate the enzyme. 3. 3. Binding of zinc ions to alkaline phosphatase induces conformational changes which impair the catalytic action of the enzyme. 4. 4. The inhibition of the enzyme by zinc ions is affected by membrane environment and magnesium ions. © 1990. | en |
| dc.description.affiliation | Departamento de Quimica, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto-USP, 14049 Ribeirão Preto, SP. Brasil [Tel. 634-6255] | |
| dc.description.affiliation | Departamento de Tecnologia, Faculdade de Ciências Agrárias e Veterinárias-UNESP, 14870 Jaboticabal, SP | |
| dc.description.affiliation | Departamento de Fisica e Química, Faculdade de Ciências Farmaceuticas-USP, 14049 Ribeirão Preto, SP | |
| dc.description.affiliationUnesp | Departamento de Tecnologia, Faculdade de Ciências Agrárias e Veterinárias-UNESP, 14870 Jaboticabal, SP | |
| dc.format.extent | 747-751 | |
| dc.identifier | http://dx.doi.org/10.1016/0020-711X(90)90010-Z | |
| dc.identifier.citation | International Journal of Biochemistry, v. 22, n. 7, p. 747-751, 1990. | |
| dc.identifier.doi | 10.1016/0020-711X(90)90010-Z | |
| dc.identifier.issn | 0020-711X | |
| dc.identifier.scopus | 2-s2.0-0025036202 | |
| dc.identifier.uri | http://hdl.handle.net/11449/223914 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | International Journal of Biochemistry | |
| dc.source | Scopus | |
| dc.title | Effect of membrane moiety and magnesium ions on the inhibition of matrix-induced alkaline phosphatase by zinc ions | en |
| dc.type | Artigo | |
| unesp.department | Tecnologia - FCAV | pt |