Expressão das caderinas nos tumores mamários em cadelas

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dc.contributor.authorPiekarz, C. H.
dc.contributor.authorBiondo, A. W.
dc.contributor.authorAmorim, Renée Laufer [UNESP]
dc.contributor.authorRodaski, S.
dc.contributor.authorBarros Filho, Ivan Roque
dc.contributor.authorDe Nardi, A. B.
dc.contributor.institutionUniversidade Federal do Paraná (UFPR)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de Franca -UNIFRAN
dc.date.accessioned2014-05-27T11:23:38Z
dc.date.available2014-05-27T11:23:38Z
dc.date.issued2008-08-04
dc.description.abstractMammary tumors are among the most common neoplasia of canine females. The occurrence of metastasis may be detected by proteic markers. Among them, exist the E-cadherin, a member of cadherin family known for its important role in the regulation of intercellular adhesion in epithelial tissues. Studies suggest that E-cadherin may function as a tumor and invasion suppressor molecule. Cadherin activity is regulated by multiple mechanisms, including interaction with other proteins such as catenins. In this review, the authors approach the cadherin family and other related adhesion proteins including its function, physiopathology and potential use as marker for diagnosis and prognosis of canine mammary tumors.en
dc.description.affiliationPós-Graduação em Ciências Veterinárias Universidade Federal do Paraná-UFPR, Curitiba, PR
dc.description.affiliationDepartamento de Medicina Veterinária UFPR, Curitiba, PR
dc.description.affiliationDepartamento de Clínica Veterinária Universidade Estadual Paulista -UNESP, Campus de Botucatu, Botucato, SP
dc.description.affiliationDepartamento de Cirurgia e Anestesiologia Veterinária Universidade de Franca -UNIFRAN, Franca
dc.description.affiliation, Rua dos Funcionários 1540, 800035-050 Curitiba, PR
dc.description.affiliationUnespDepartamento de Clínica Veterinária Universidade Estadual Paulista -UNESP, Campus de Botucatu, Botucato, SP
dc.format.extent13-21
dc.identifierhttp://ojs.c3sl.ufpr.br/ojs/index.php/veterinary/article/view/11533
dc.identifier.citationArchives of Veterinary Science, v. 13, n. 1, p. 13-21, 2008.
dc.identifier.file2-s2.0-48249141497.pdf
dc.identifier.issn1517-784X
dc.identifier.lattes9795829022108105
dc.identifier.scopus2-s2.0-48249141497
dc.identifier.urihttp://hdl.handle.net/11449/70524
dc.language.isopor
dc.relation.ispartofArchives of Veterinary Science
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCadherin
dc.subjectDog
dc.subjectImmunohistochemistry
dc.subjectMammary neoplasi
dc.subjectCanis familiaris
dc.titleExpressão das caderinas nos tumores mamários em cadelaspt
dc.title.alternativeCadherin expression in canine mammary tumorsen
dc.typeArtigo
dcterms.licensehttp://ojs.c3sl.ufpr.br/ojs2/index.php/veterinary/about/editorialPolicies#openAccessPolicy
unesp.author.lattes9795829022108105
unesp.author.lattes5256503293611165[6]
unesp.author.orcid0000-0001-6463-2144[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
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Artigos - Clínica Veterinária - FMVZ