Methods for qualitative analysis of cefazolin sodium raw material and pharmaceutical product

dc.contributor.authorPedroso, Tahisa Marcela [UNESP]
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-01-28T16:56:42Z
dc.date.available2016-01-28T16:56:42Z
dc.date.issued2013
dc.description.abstractIn this work we studied qualitative methods for analysis and identification of cefazolin sodium, β-lactam antimicrobial for parenteral use, belonging to the group of first-generation cephalosporin, used as a therapeutic agent and for the surgical prophylaxis, in the pharmaceutical form of powder lyophilized for injectable solution. Qualitative analysis was performed by solubility, melting point, pH determination, thin layer chromatography, ultraviolet spectroscopy, infrared spectroscopy and high performance liquid chromatography, allowing the identification of sample. These methods were reproducible and quick to identify cefazolin sodium, which can be used routinely in analysis of quality control in pharmaceutical laboratories.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Farmacêuticas de Araraquara (FCFAR), Departamento de Farmacos e Médicamentos, Rodovia Araraquara-Jaú, km 1, Campus, CEP 14801-902, Araraquara, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Farmacêuticas de Araraquara (FCFAR), Departamento de Farmacos e Médicamentos, Rodovia Araraquara-Jaú, km 1, Campus, CEP 14801-902, Araraquara, SP, Brasil
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent29-38
dc.identifierhttp://dx.doi.org/10.5923/j.pc.20130302.01
dc.identifier.citationPhysical Chemistry, v. 3, n. 2, p. 29-38, 2013.
dc.identifier.doi10.5923/j.pc.20130302.01
dc.identifier.issn2167-7069
dc.identifier.lattes4238972287355427
dc.identifier.lattes9881720291571774
dc.identifier.urihttp://hdl.handle.net/11449/133813
dc.language.isoeng
dc.publisherScientific and Academic Publishing
dc.relation.ispartofPhysical Chemistry
dc.rights.accessRightsAcesso restrito
dc.sourceCurrículo Lattes
dc.subjectCefazolin sodiumen
dc.subjectCephalosporinen
dc.subjectAnalytical methoden
dc.subjectQualitative analysisen
dc.subjectQuality controlen
dc.titleMethods for qualitative analysis of cefazolin sodium raw material and pharmaceutical producten
dc.typeArtigo
dcterms.rightsHolderScientific and Academic Publishing
unesp.author.lattes4238972287355427
unesp.author.lattes9881720291571774
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentospt

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