Methods for qualitative analysis of cefazolin sodium raw material and pharmaceutical product
dc.contributor.author | Pedroso, Tahisa Marcela [UNESP] | |
dc.contributor.author | Salgado, Hérida Regina Nunes [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2016-01-28T16:56:42Z | |
dc.date.available | 2016-01-28T16:56:42Z | |
dc.date.issued | 2013 | |
dc.description.abstract | In this work we studied qualitative methods for analysis and identification of cefazolin sodium, β-lactam antimicrobial for parenteral use, belonging to the group of first-generation cephalosporin, used as a therapeutic agent and for the surgical prophylaxis, in the pharmaceutical form of powder lyophilized for injectable solution. Qualitative analysis was performed by solubility, melting point, pH determination, thin layer chromatography, ultraviolet spectroscopy, infrared spectroscopy and high performance liquid chromatography, allowing the identification of sample. These methods were reproducible and quick to identify cefazolin sodium, which can be used routinely in analysis of quality control in pharmaceutical laboratories. | en |
dc.description.affiliation | Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Farmacêuticas de Araraquara (FCFAR), Departamento de Farmacos e Médicamentos, Rodovia Araraquara-Jaú, km 1, Campus, CEP 14801-902, Araraquara, SP, Brasil | |
dc.description.affiliationUnesp | Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Farmacêuticas de Araraquara (FCFAR), Departamento de Farmacos e Médicamentos, Rodovia Araraquara-Jaú, km 1, Campus, CEP 14801-902, Araraquara, SP, Brasil | |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.format.extent | 29-38 | |
dc.identifier | http://dx.doi.org/10.5923/j.pc.20130302.01 | |
dc.identifier.citation | Physical Chemistry, v. 3, n. 2, p. 29-38, 2013. | |
dc.identifier.doi | 10.5923/j.pc.20130302.01 | |
dc.identifier.issn | 2167-7069 | |
dc.identifier.lattes | 4238972287355427 | |
dc.identifier.lattes | 9881720291571774 | |
dc.identifier.uri | http://hdl.handle.net/11449/133813 | |
dc.language.iso | eng | |
dc.publisher | Scientific and Academic Publishing | |
dc.relation.ispartof | Physical Chemistry | |
dc.rights.accessRights | Acesso restrito | |
dc.source | Currículo Lattes | |
dc.subject | Cefazolin sodium | en |
dc.subject | Cephalosporin | en |
dc.subject | Analytical method | en |
dc.subject | Qualitative analysis | en |
dc.subject | Quality control | en |
dc.title | Methods for qualitative analysis of cefazolin sodium raw material and pharmaceutical product | en |
dc.type | Artigo | |
dcterms.rightsHolder | Scientific and Academic Publishing | |
unesp.author.lattes | 4238972287355427 | |
unesp.author.lattes | 9881720291571774 | |
unesp.campus | Universidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquara | pt |
unesp.department | Fármacos e Medicamentos - FCF | pt |