Effects of Formulations Containing Dimethylaminoethanol (DMAE) Acetoamidobenzoate and Pidolate on the Skin

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dc.contributor.authorGuimaraes, Gustavo N.
dc.contributor.authorChorilli, Marlus [UNESP]
dc.contributor.authorLeonardi, Gislaine R.
dc.contributor.authorPrestes, Paula S.
dc.contributor.authorGarcia, Gislene
dc.contributor.authorPires-De-Campos, Maria S. M.
dc.contributor.authorPolacow, Maria L. O.
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Methodist Piracicaba
dc.date.accessioned2014-05-20T13:24:51Z
dc.date.available2014-05-20T13:24:51Z
dc.date.issued2011-05-01
dc.description.abstractThe aim of this study was to analyze the effects of formulations containing DMAE pidolate and DMAE acetoamidobenzoate on the skin. Four areas of five swines were submitted to following treatments during 15 days: C (Control), S (Silicone = 80 % DC*LC Blend (R)), F1 (DMAE acetoamidobenzoate), F2 (DMAE pidolate). Measures of the thickness of epidermis and stratum corneum, and the density population of fibroblasts and leukocytes in papillary dermis were obtained. We also assessed possible variations in birefringence of dermis collagen bundles. Means of the data was compared using ANOVA followed by the Tukey test. The F1 and F2 groups showed a thicker epidermis than the control group (p < 0.01), but did not demonstrate a significant difference in the number of fibroblasts and leukocytes, as well as in the birefringent areas of collagen bundles, in comparison with the control groups. The DMAE-supplemented formulations enhanced viable epidermis thickness, but did not modify structures related with mechanical properties of the skin.en
dc.description.affiliationUniv Estadual Campinas, Dept Morphol, Piracicaba Dent Sch, BR-13414903 Piracicaba, SP, Brazil
dc.description.affiliationSão Paulo State Univ, Dept Drugs & Med, Fac Pharmaceut Sci Araraquara, São Paulo, SP, Brazil
dc.description.affiliationUniv Methodist Piracicaba, Fac Hlth Sci, Piracicaba, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Dept Drugs & Med, Fac Pharmaceut Sci Araraquara, São Paulo, SP, Brazil
dc.format.extent641-646
dc.identifierhttp://sedici.unlp.edu.ar/bitstream/handle/10915/8195/Resumen.pdf?sequence=1
dc.identifier.citationLatin American Journal of Pharmacy. La Plata: Colegio Farmaceuticos Provincia de Buenos Aires, v. 30, n. 4, p. 641-646, 2011.
dc.identifier.issn0326-2383
dc.identifier.urihttp://hdl.handle.net/11449/7815
dc.identifier.wosWOS:000294752700003
dc.language.isoeng
dc.publisherColegio Farmaceuticos Provincia de Buenos Aires
dc.relation.ispartofLatin American Journal of Pharmacy
dc.relation.ispartofjcr0.401
dc.relation.ispartofsjr0,152
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectDimethylaminoethanolen
dc.subjectHistopatologyen
dc.subjectSkinen
dc.titleEffects of Formulations Containing Dimethylaminoethanol (DMAE) Acetoamidobenzoate and Pidolate on the Skinen
dc.typeArtigo
dcterms.rightsHolderColegio Farmaceuticos Provincia de Buenos Aires
unesp.author.orcid0000-0002-6698-0545[2]
unesp.author.orcid0000-0002-7126-1326[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas